decreased Paneth cell number_Cyld<tm1.1Mpa>/Cyld<tm1.1Mpa>,Fadd<tm1Mpa>/Fadd<tm1Mpa>,Tg(Vil1-cre)997Gum/0

http://metadb.riken.jp/0013486B6CgFaddtm1MpaCyldtm11MpaTgVil1cre997GumCyldtm11MpaCyldtm11MpaFaddtm1MpaFaddtm1MpaTgVil1cre997Gum0Faddtm1MpaTgVil1cre997GumCyldtm11Mpa

decreased Paneth cell number_Cyld<tm1.1Mpa>/Cyld<tm1.1Mpa>,Fadd<tm1Mpa>/Fadd<tm1Mpa>,Tg(Vil1-cre)997Gum/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CYLD lysine 63 deubiquitinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1921506
• Fas (TNFRSF6)-associated via death domain
  http://metadb.riken.jp/db/mgi_rdf/MGI:109324
• transgene insertion 997, Deborah L Gumucio
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446957

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cyld<tm1.1Mpa>/Cyld<tm1.1Mpa>,Fadd<tm1Mpa>/Fadd<tm1Mpa>,Tg(Vil1-cre)997Gum/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fadd<tm1Mpa>|Tg(Vil1-cre)997Gum|Cyld<tm1.1Mpa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.Cg-Fadd<tm1Mpa> Cyld<tm1.1Mpa> Tg(Vil1-cre)997Gum

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased Paneth cell number
  http://purl.obolibrary.org/obo/MP_0013486

文献

http://purl.org/net/cito/citesAsAuthority

• Patrick-Simon. Welz, et.al., FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation., Nature, 2011, 477
  http://rdf.ncbi.nlm.nih.gov/pubmed/21804564