decreased Paneth cell number_Fadd<tm1Mpa>/Fadd<tm1Mpa>,Tnf<tm1Gkl>/Tnf<tm1Gkl>,Tg(Vil1-cre)997Gum/0

http://metadb.riken.jp/0013486B6CgFaddtm1MpaTnftm1GklTgVil1cre997GumFaddtm1MpaFaddtm1MpaTnftm1GklTnftm1GklTgVil1cre997Gum0TgVil1cre997GumTnftm1GklFaddtm1Mpa

decreased Paneth cell number_Fadd<tm1Mpa>/Fadd<tm1Mpa>,Tnf<tm1Gkl>/Tnf<tm1Gkl>,Tg(Vil1-cre)997Gum/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tumor necrosis factor
  http://metadb.riken.jp/db/mgi_rdf/MGI:104798
• Fas (TNFRSF6)-associated via death domain
  http://metadb.riken.jp/db/mgi_rdf/MGI:109324
• transgene insertion 997, Deborah L Gumucio
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446957

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fadd<tm1Mpa>/Fadd<tm1Mpa>,Tnf<tm1Gkl>/Tnf<tm1Gkl>,Tg(Vil1-cre)997Gum/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Vil1-cre)997Gum|Tnf<tm1Gkl>|Fadd<tm1Mpa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.Cg-Fadd<tm1Mpa> Tnf<tm1Gkl> Tg(Vil1-cre)997Gum

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased Paneth cell number
  http://purl.obolibrary.org/obo/MP_0013486

文献

http://purl.org/net/cito/citesAsAuthority

• Patrick-Simon. Welz, et.al., FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation., Nature, 2011, 477
  http://rdf.ncbi.nlm.nih.gov/pubmed/21804564