decreased Paneth cell number_Slc39a7<tm1.1Tfk>/Slc39a7<tm1.1Tfk>,Lgr5<tm1(cre/ERT2)Cle>/Lgr5<+>

http://metadb.riken.jp/0013486I129P2OlaHsd129S1Sv129X1SvJC57BL6Slc39a7tm11TfkSlc39a7tm11TfkLgr5tm1creERT2CleLgr5Lgr5Slc39a7tm11TfkLgr5tm1creERT2Cle

decreased Paneth cell number_Slc39a7<tm1.1Tfk>/Slc39a7<tm1.1Tfk>,Lgr5<tm1(cre/ERT2)Cle>/Lgr5<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• leucine rich repeat containing G protein coupled receptor 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1341817
• solute carrier family 39 (zinc transporter), member 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:95909

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Slc39a7<tm1.1Tfk>/Slc39a7<tm1.1Tfk>,Lgr5<tm1(cre/ERT2)Cle>/Lgr5<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lgr5<+>|Slc39a7<tm1.1Tfk>|Lgr5<tm1(cre/ERT2)Cle>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased Paneth cell number
  http://purl.obolibrary.org/obo/MP_0013486

文献

http://purl.org/net/cito/citesAsAuthority

• Wakana. Ohashi, et.al., Zinc Transporter SLC39A7/ZIP7 Promotes Intestinal Epithelial Self-Renewal by Resolving ER Stress., PLoS genetics, 2016, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/27736879