increased fibroblast apoptosis_Ewsr1<tm2(FLI1*)Sblee>/Ewsr1<+>,Tg(CAG-cre/Esr1*)5Amc/0

http://metadb.riken.jp/0013501I129S6SvEvTacC57BL6CBAEwsr1tm2FLI1SbleeEwsr1TgCAGcreEsr15Amc0TgCAGcreEsr15AmcEwsr1tm2FLI1SbleeEwsr1

increased fibroblast apoptosis_Ewsr1<tm2(FLI1*)Sblee>/Ewsr1<+>,Tg(CAG-cre/Esr1*)5Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 5, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182765
• Ewing sarcoma breakpoint region 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99960

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ewsr1<tm2(FLI1*)Sblee>/Ewsr1<+>,Tg(CAG-cre/Esr1*)5Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CAG-cre/Esr1*)5Amc|Ewsr1<tm2(FLI1*)Sblee>|Ewsr1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased fibroblast apoptosis
  http://purl.obolibrary.org/obo/MP_0013501

文献

http://purl.org/net/cito/citesAsAuthority

• Eun Jung. Sohn, et.al., EWS/FLI1 oncogene activates caspase 3 transcription and triggers apoptosis in vivo., Cancer research, 2010, 70
  http://rdf.ncbi.nlm.nih.gov/pubmed/20103643