increased embryonic tissue cell apoptosis_Brca1<tm2.1Cxd>/Brca1<tm2.1Cxd>,Trp53<tm1Brd>/Trp53<+>

http://metadb.riken.jp/0013504I129S6SvEvTac129S7SvEvBrdBrca1tm21CxdBrca1tm21CxdTrp53tm1BrdTrp53Brca1tm21CxdTrp53tm1BrdTrp53

increased embryonic tissue cell apoptosis_Brca1<tm2.1Cxd>/Brca1<tm2.1Cxd>,Trp53<tm1Brd>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• breast cancer 1, early onset
  http://metadb.riken.jp/db/mgi_rdf/MGI:104537
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Brca1<tm2.1Cxd>/Brca1<tm2.1Cxd>,Trp53<tm1Brd>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Brca1<tm2.1Cxd>|Trp53<tm1Brd>|Trp53<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * 129S7/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased embryonic tissue cell apoptosis
  http://purl.obolibrary.org/obo/MP_0013504

文献

http://purl.org/net/cito/citesAsAuthority

• X. Xu, et.al., Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis., Nature genetics, 2001, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/11431698