increased B cell acute lymphoblastic leukemia incidence_Pax5<tm3Mbu>/Pax5<+>,Tcf3<tm1(PBX1)Mlc>/Tcf3<+>,Cd19<tm1(cre)Cgn>/Cd19<+>

http://metadb.riken.jp/0014050I129P2OlaHsdC57BL6Pax5tm3MbuPax5Tcf3tm1PBX1MlcTcf3Cd19tm1creCgnCd19Pax5tm3MbuCd19tm1creCgnPax5Cd19Tcf3tm1PBX1MlcTcf3

increased B cell acute lymphoblastic leukemia incidence_Pax5<tm3Mbu>/Pax5<+>,Tcf3<tm1(PBX1)Mlc>/Tcf3<+>,Cd19<tm1(cre)Cgn>/Cd19<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transcription factor 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:98510
• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319
• paired box 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:97489

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pax5<tm3Mbu>/Pax5<+>,Tcf3<tm1(PBX1)Mlc>/Tcf3<+>,Cd19<tm1(cre)Cgn>/Cd19<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pax5<tm3Mbu>|Cd19<tm1(cre)Cgn>|Pax5<+>|Cd19<+>|Tcf3<tm1(PBX1)Mlc>|Tcf3<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• http://purl.obolibrary.org/obo/MP_0014050

文献

http://purl.org/net/cito/citesAsAuthority

• Jesús. Duque-Afonso, et.al., Comparative genomics reveals multistep pathogenesis of E2A-PBX1 acute lymphoblastic leukemia., The Journal of clinical investigation, 2015, 125
  http://rdf.ncbi.nlm.nih.gov/pubmed/26301816