increased pancreatic islet cell apoptosis_Atf6<tm1Hota>/Atf6<tm1Hota>,Tg(Ins2-cre)25Mgn/0

http://metadb.riken.jp/0014121B6CgAtf6tm1HotaTgIns2cre25MgnAtf6tm1HotaAtf6tm1HotaTgIns2cre25Mgn0Atf6tm1HotaTgIns2cre25Mgn

increased pancreatic islet cell apoptosis_Atf6<tm1Hota>/Atf6<tm1Hota>,Tg(Ins2-cre)25Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• activating transcription factor 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926157
• transgene insertion 25, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176225

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Atf6<tm1Hota>/Atf6<tm1Hota>,Tg(Ins2-cre)25Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Atf6<tm1Hota>|Tg(Ins2-cre)25Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.Cg-Atf6<tm1Hota> Tg(Ins2-cre)25Mgn

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• http://purl.obolibrary.org/obo/MP_0014121

文献

http://purl.org/net/cito/citesAsAuthority

• Feyza. Engin, et.al., Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes., Science translational medicine, 2013, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/24225943