decreased thyroid gland weight_Thrb<tm1Mkni>/Thrb<+>,Hprt<tm1(TG-cre)1Sasr>/Y

http://metadb.riken.jp/0020168IC57BL6Thrbtm1MkniThrbHprttm1TGcre1SasrYHprttm1TGcre1SasrThrbThrbtm1Mkni

decreased thyroid gland weight_Thrb<tm1Mkni>/Thrb<+>,Hprt<tm1(TG-cre)1Sasr>/Y

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• thyroid hormone receptor beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:98743
• hypoxanthine guanine phosphoribosyl transferase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96217

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Thrb<tm1Mkni>/Thrb<+>,Hprt<tm1(TG-cre)1Sasr>/Y

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hprt<tm1(TG-cre)1Sasr>|Thrb<+>|Thrb<tm1Mkni>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased thyroid gland weight
  http://purl.obolibrary.org/obo/MP_0020168

文献

http://purl.org/net/cito/citesAsAuthority

• Samia. Selmi-Ruby, et.al., The targeted inactivation of TRβ gene in thyroid follicular cells suggests a new mechanism of regulation of thyroid hormone production., Endocrinology, 2014, 155
  http://rdf.ncbi.nlm.nih.gov/pubmed/24265449