X. Yang, et.al., Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta., The EMBO journal, 1999, 18

http://rdf.ncbi.nlm.nih.gov/pubmed/10064594

X. Yang, et.al., Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta., The EMBO journal, 1999, 18

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Smad3<tm1Cxd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1857695

class

http://purl.org/net/cito/citesAsAuthority

• Smad3<tm1Cxd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1857695

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• kyphosis_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0000160EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• decreased body size_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0001265EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• abnormal thymus involution_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0001824EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• small spleen_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0000692EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• increased leukocyte cell number_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0000218EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• abnormal immune system morphology_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0000685EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• impaired neutrophil chemotaxis_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0008720EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• increased inflammatory response_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0001846EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• increased monocyte cell number_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0000220EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• spleen hypoplasia_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0000694EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• abnormal T cell physiology_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0002444EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• pancreas inflammation_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0001869EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• premature death_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0002083EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• increased intestinal adenocarcinoma incidence_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0002957EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• extramedullary hematopoiesis_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0000240EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• enlarged lymph nodes_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0000702EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• stomach inflammation_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0001873EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• enlarged mesenteric lymph nodes_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0008466EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• small intestinal inflammation_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0003306EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• increased neutrophil cell number_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0000219EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• thymus hypoplasia_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0001823EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• abnormal T cell activation_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0001828EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd
• colitis_Smad3<tm1Cxd>/Smad3<tm1Cxd>
  http://metadb.riken.jp/0002816EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmad3tm1CxdSmad3tm1CxdSmad3tm1Cxd