D. Feldmeyer, et.al., Neurological dysfunctions in mice expressing different levels of the Q/R site-unedited AMPAR subunit GluR-B., Nature neuroscience, 1999, 2

http://rdf.ncbi.nlm.nih.gov/pubmed/10195181

D. Feldmeyer, et.al., Neurological dysfunctions in mice expressing different levels of the Q/R site-unedited AMPAR subunit GluR-B., Nature neuroscience, 1999, 2

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gria2<tm2.1Rsp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2178122
• Tg(Gria2*586N)238.2Rsp
  http://metadb.riken.jp/db/mgi_rdf/MGI:3612450
• Gria2<tm2Rsp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2178121

class

http://purl.org/net/cito/citesAsAuthority

• Gria2<tm2.1Rsp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2178122
• Tg(Gria2*586N)238.2Rsp
  http://metadb.riken.jp/db/mgi_rdf/MGI:3612450
• Gria2<tm2Rsp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2178121

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• lethargy_Gria2<tm2Rsp>/Gria2<tm2Rsp>
  http://metadb.riken.jp/0005202I129S1Sv129X1SvJGria2tm2RspGria2tm2RspGria2tm2Rsp
• postnatal growth retardation_Gria2<tm2Rsp>/Gria2<tm2Rsp>
  http://metadb.riken.jp/0001732I129S1Sv129X1SvJGria2tm2RspGria2tm2RspGria2tm2Rsp
• abnormal AMPA-mediated synaptic currents_Gria2<tm2Rsp>/Gria2<+>,Tg(Gria2*586N)238.2Rsp/0
  http://metadb.riken.jp/0002885I129S1Sv129X1SvJGria2tm2RspGria2TgGria2586N2382Rsp0Gria2TgGria2586N2382RspGria2tm2Rsp
• abnormal AMPA-mediated synaptic currents_Gria2<tm2.1Rsp>/Gria2<+>
  http://metadb.riken.jp/0002885I129S1Sv129X1SvJGria2tm21RspGria2Gria2Gria2tm21Rsp
• abnormal AMPA-mediated synaptic currents_Tg(Gria2*586N)238.2Rsp/0
  http://metadb.riken.jp/0002885NSTgGria2586N2382Rsp0TgGria2586N2382Rsp
• postnatal lethality, complete penetrance_Gria2<tm2Rsp>/Gria2<tm2Rsp>
  http://metadb.riken.jp/0011085I129S1Sv129X1SvJGria2tm2RspGria2tm2RspGria2tm2Rsp
• abnormal AMPA-mediated synaptic currents_Gria2<tm2Rsp>/Gria2<tm2Rsp>
  http://metadb.riken.jp/0002885I129S1Sv129X1SvJGria2tm2RspGria2tm2RspGria2tm2Rsp
• decreased body weight_Gria2<tm2.1Rsp>/Gria2<+>
  http://metadb.riken.jp/0001262I129S1Sv129X1SvJGria2tm21RspGria2Gria2Gria2tm21Rsp
• postnatal lethality, complete penetrance_Gria2<tm2.1Rsp>/Gria2<+>
  http://metadb.riken.jp/0011085I129S1Sv129X1SvJGria2tm21RspGria2Gria2Gria2tm21Rsp
• decreased body weight_Gria2<tm2Rsp>/Gria2<tm2Rsp>
  http://metadb.riken.jp/0001262I129S1Sv129X1SvJGria2tm2RspGria2tm2RspGria2tm2Rsp
• seizures_Gria2<tm2.1Rsp>/Gria2<+>
  http://metadb.riken.jp/0002064I129S1Sv129X1SvJGria2tm21RspGria2Gria2Gria2tm21Rsp
• seizures_Gria2<tm2Rsp>/Gria2<+>,Tg(Gria2*586N)238.2Rsp/0
  http://metadb.riken.jp/0002064I129S1Sv129X1SvJGria2tm2RspGria2TgGria2586N2382Rsp0Gria2TgGria2586N2382RspGria2tm2Rsp
• motor neuron degeneration_Tg(Gria2*586N)238.2Rsp/0
  http://metadb.riken.jp/0000938NSTgGria2586N2382Rsp0TgGria2586N2382Rsp
• premature death_Gria2<tm2Rsp>/Gria2<+>,Tg(Gria2*586N)238.2Rsp/0
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJGria2tm2RspGria2TgGria2586N2382Rsp0Gria2TgGria2586N2382RspGria2tm2Rsp
• abnormal hippocampus CA3 region morphology_Gria2<tm2Rsp>/Gria2<tm2Rsp>
  http://metadb.riken.jp/0008267I129S1Sv129X1SvJGria2tm2RspGria2tm2RspGria2tm2Rsp
• abnormal motor capabilities/coordination/movement_Gria2<tm2.1Rsp>/Gria2<+>
  http://metadb.riken.jp/0002066I129S1Sv129X1SvJGria2tm21RspGria2Gria2Gria2tm21Rsp
• abnormal hippocampus CA3 region morphology_Gria2<tm2.1Rsp>/Gria2<+>
  http://metadb.riken.jp/0008267I129S1Sv129X1SvJGria2tm21RspGria2Gria2Gria2tm21Rsp
• abnormal hippocampus CA3 region morphology_Gria2<tm2Rsp>/Gria2<+>,Tg(Gria2*586N)238.2Rsp/0
  http://metadb.riken.jp/0008267I129S1Sv129X1SvJGria2tm2RspGria2TgGria2586N2382Rsp0Gria2TgGria2586N2382RspGria2tm2Rsp
• abnormal AMPA-mediated synaptic currents_Gria2<tm2Rsp>/Gria2<+>
  http://metadb.riken.jp/0002885I129S1Sv129X1SvJGria2tm2RspGria2Gria2Gria2tm2Rsp
• abnormal excitatory postsynaptic potential_Gria2<tm2Rsp>/Gria2<tm2Rsp>
  http://metadb.riken.jp/0002912I129S1Sv129X1SvJGria2tm2RspGria2tm2RspGria2tm2Rsp
• premature death_Gria2<tm2Rsp>/Gria2<+>
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJGria2tm2RspGria2Gria2Gria2tm2Rsp
• abnormal motor capabilities/coordination/movement_Gria2<tm2Rsp>/Gria2<+>,Tg(Gria2*586N)238.2Rsp/0
  http://metadb.riken.jp/0002066I129S1Sv129X1SvJGria2tm2RspGria2TgGria2586N2382Rsp0Gria2TgGria2586N2382RspGria2tm2Rsp

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD21674
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD21674
• CD40718
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD40718