D. Kontoyiannis, et.al., Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut-associated immunopathologies., Immunity, 1999, 10

http://rdf.ncbi.nlm.nih.gov/pubmed/10204494

D. Kontoyiannis, et.al., Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut-associated immunopathologies., Immunity, 1999, 10

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tnf<tm2.1Gkl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3625620
• Tnf<tm2Gkl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388715

class

http://purl.org/net/cito/citesAsAuthority

• Tnf<tm2.1Gkl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3625620
• Tnf<tm2Gkl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388715

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• small intestinal inflammation_Tnf<tm2Gkl>/Tnf<+>
  http://metadb.riken.jp/0003306I129SSvEvC57BL6Tnftm2GklTnfTnfTnftm2Gkl
• rheumatoid arthritis_Tnf<tm1Gkl>/Tnf<tm2Gkl>
  http://metadb.riken.jp/0003561I129SSvEvC57BL6Tnftm1GklTnftm2GklTnftm2GklTnftm1Gkl
• rheumatoid arthritis_Rag1<tm1Mom>/Rag1<tm1Mom>,Tnf<tm2Gkl>/Tnf<+>
  http://metadb.riken.jp/0003561I129SSvEv129S7SvEvBrdC57BL6Rag1tm1MomRag1tm1MomTnftm2GklTnfTnfTnftm2GklRag1tm1Mom
• rheumatoid arthritis_Tnf<tm2Gkl>/Tnf<+>,Tnfrsf1b<tm1Mwm>/Tnfrsf1b<tm1Mwm>
  http://metadb.riken.jp/0003561I129SSvEv129S2SvPasC57BL6Tnftm2GklTnfTnfrsf1btm1MwmTnfrsf1btm1MwmTnftm2GklTnfrsf1btm1MwmTnf
• increased circulating tumor necrosis factor level_Tnf<tm2Gkl>/Tnf<+>
  http://metadb.riken.jp/0008553I129SSvEvC57BL6Tnftm2GklTnfTnfTnftm2Gkl
• increased circulating tumor necrosis factor level_Tnf<tm2Gkl>/Tnf<tm2Gkl>,Tnfrsf1a<tm1Blt>/Tnfrsf1a<tm1Blt>
  http://metadb.riken.jp/0008553I129P2OlaHsd129SSvEvC57BL6Tnftm2GklTnftm2GklTnfrsf1atm1BltTnfrsf1atm1BltTnfrsf1atm1BltTnftm2Gkl
• small intestinal inflammation_Rag1<tm1Mom>/Rag1<tm1Mom>,Tnf<tm2Gkl>/Tnf<+>
  http://metadb.riken.jp/0003306I129SSvEv129S7SvEvBrdC57BL6Rag1tm1MomRag1tm1MomTnftm2GklTnfTnfTnftm2GklRag1tm1Mom
• increased susceptibility to endotoxin shock_Tnf<tm1Gkl>/Tnf<tm2Gkl>
  http://metadb.riken.jp/0008735I129SSvEvC57BL6Tnftm1GklTnftm2GklTnftm2GklTnftm1Gkl
• rheumatoid arthritis_Tnf<tm2Gkl>/Tnf<tm2Gkl>
  http://metadb.riken.jp/0003561I129SSvEvC57BL6Tnftm2GklTnftm2GklTnftm2Gkl
• premature death_Tnf<tm2Gkl>/Tnf<tm2Gkl>
  http://metadb.riken.jp/0002083I129SSvEvC57BL6Tnftm2GklTnftm2GklTnftm2Gkl
• increased tumor necrosis factor secretion_Tnf<tm1Gkl>/Tnf<tm2Gkl>
  http://metadb.riken.jp/0008560I129SSvEvC57BL6Tnftm1GklTnftm2GklTnftm2GklTnftm1Gkl
• small intestinal inflammation_Tnf<tm2Gkl>/Tnf<+>,Tnfrsf1b<tm1Mwm>/Tnfrsf1b<tm1Mwm>
  http://metadb.riken.jp/0003306I129SSvEv129S2SvPasC57BL6Tnftm2GklTnfTnfrsf1btm1MwmTnfrsf1btm1MwmTnftm2GklTnfrsf1btm1MwmTnf
• increased tumor necrosis factor secretion_Tnf<tm2Gkl>/Tnf<tm2Gkl>,Tnfrsf1a<tm1Blt>/Tnfrsf1a<tm1Blt>
  http://metadb.riken.jp/0008560I129P2OlaHsd129SSvEvC57BL6Tnftm2GklTnftm2GklTnfrsf1atm1BltTnfrsf1atm1BltTnfrsf1atm1BltTnftm2Gkl
• increased circulating tumor necrosis factor level_Tnf<tm2Gkl>/Tnf<tm2Gkl>
  http://metadb.riken.jp/0008553I129SSvEvC57BL6Tnftm2GklTnftm2GklTnftm2Gkl
• thymus hypoplasia_Tnf<tm2Gkl>/Tnf<tm2Gkl>
  http://metadb.riken.jp/0001823I129SSvEvC57BL6Tnftm2GklTnftm2GklTnftm2Gkl
• rheumatoid arthritis_Tnf<tm2Gkl>/Tnf<+>
  http://metadb.riken.jp/0003561I129SSvEvC57BL6Tnftm2GklTnfTnfTnftm2Gkl
• increased circulating tumor necrosis factor level_Tnf<tm1Gkl>/Tnf<tm2Gkl>
  http://metadb.riken.jp/0008553I129SSvEvC57BL6Tnftm1GklTnftm2GklTnftm2GklTnftm1Gkl
• small intestinal inflammation_Tnf<tm2Gkl>/Tnf<tm2Gkl>
  http://metadb.riken.jp/0003306I129SSvEvC57BL6Tnftm2GklTnftm2GklTnftm2Gkl
• decreased body weight_Tnf<tm2Gkl>/Tnf<tm2Gkl>
  http://metadb.riken.jp/0001262I129SSvEvC57BL6Tnftm2GklTnftm2GklTnftm2Gkl