S. Giroux, et.al., Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta., Current biology : CB, 1999, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/10209122

S. Giroux, et.al., Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta., Current biology : CB, 1999, 9

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Map2k1<Gt(ROSABetageo)J2Chrn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2178132

class

http://purl.org/net/cito/citesAsAuthority

• Map2k1<Gt(ROSABetageo)J2Chrn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2178132

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal placental labyrinth vasculature morphology_Map2k1<Gt(ROSABetageo)J2Chrn>/Map2k1<Gt(ROSABetageo)J2Chrn>
  http://metadb.riken.jp/0008803I129Sv129SSvEvC57BL6JSJLMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2Chrn
• abnormal vascular endothelial cell migration_Map2k1<Gt(ROSABetageo)J2Chrn>/Map2k1<Gt(ROSABetageo)J2Chrn>
  http://metadb.riken.jp/0003544I129Sv129SSvEvC57BL6JSJLMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2Chrn
• decreased embryo size_Map2k1<Gt(ROSABetageo)J2Chrn>/Map2k1<Gt(ROSABetageo)J2Chrn>
  http://metadb.riken.jp/0001698I129Sv129SSvEvC57BL6JSJLMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2Chrn
• abnormal spongiotrophoblast layer morphology_Map2k1<Gt(ROSABetageo)J2Chrn>/Map2k1<Gt(ROSABetageo)J2Chrn>
  http://metadb.riken.jp/0004255I129Sv129SSvEvC57BL6JSJLMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2Chrn
• pale yolk sac_Map2k1<Gt(ROSABetageo)J2Chrn>/Map2k1<Gt(ROSABetageo)J2Chrn>
  http://metadb.riken.jp/0001722I129Sv129SSvEvC57BL6JSJLMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2Chrn
• abnormal placenta labyrinth morphology_Map2k1<Gt(ROSABetageo)J2Chrn>/Map2k1<Gt(ROSABetageo)J2Chrn>
  http://metadb.riken.jp/0001716I129Sv129SSvEvC57BL6JSJLMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2Chrn
• abnormal angiogenesis_Map2k1<Gt(ROSABetageo)J2Chrn>/Map2k1<Gt(ROSABetageo)J2Chrn>
  http://metadb.riken.jp/0000260I129Sv129SSvEvC57BL6JSJLMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2Chrn
• abnormal cell migration_Map2k1<Gt(ROSABetageo)J2Chrn>/Map2k1<Gt(ROSABetageo)J2Chrn>
  http://metadb.riken.jp/0003091I129Sv129SSvEvC57BL6JSJLMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2Chrn
• embryonic lethality during organogenesis, incomplete penetrance_Map2k1<Gt(ROSABetageo)J2Chrn>/Map2k1<Gt(ROSABetageo)J2Chrn>
  http://metadb.riken.jp/0011108I129Sv129SSvEvC57BL6JSJLMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2Chrn
• embryo tissue necrosis_Map2k1<Gt(ROSABetageo)J2Chrn>/Map2k1<Gt(ROSABetageo)J2Chrn>
  http://metadb.riken.jp/0013241I129Sv129SSvEvC57BL6JSJLMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2ChrnMap2k1GtROSABetageoJ2Chrn