C A. Chambers, et.al., Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4(+) T cell responses., Proceedings of the National Academy of Sciences of the United States of America, 1999, 96

http://rdf.ncbi.nlm.nih.gov/pubmed/10411922

C A. Chambers, et.al., Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4(+) T cell responses., Proceedings of the National Academy of Sciences of the United States of America, 1999, 96

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased interleukin-4 secretion_Ctla4<tm1All>/Ctla4<tm1All>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0008699I129SSv129X1SvJC57BL6SJLCtla4tm1AllCtla4tm1AllRag1tm1MomRag1tm1MomTgTcrAND53Hed0TgTcrAND53HedRag1tm1MomCtla4tm1All
• abnormal T cell activation_Ctla4<tm1All>/Ctla4<tm1All>,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0001828I129S1Sv129X1SvJC57BL6SJLCtla4tm1AllCtla4tm1AllTgTcrAND53Hed0Ctla4tm1AllTgTcrAND53Hed
• increased CD4-positive, alpha beta T cell number_Ctla4<tm1All>/Ctla4<tm1All>,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0008074I129S1Sv129X1SvJC57BL6SJLCtla4tm1AllCtla4tm1AllTgTcrAND53Hed0Ctla4tm1AllTgTcrAND53Hed
• increased T cell proliferation_Ctla4<tm1All>/Ctla4<tm1All>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0005348I129SSv129X1SvJC57BL6SJLCtla4tm1AllCtla4tm1AllRag1tm1MomRag1tm1MomTgTcrAND53Hed0TgTcrAND53HedRag1tm1MomCtla4tm1All
• increased CD8-positive, alpha-beta T cell number_Ctla4<tm1All>/Ctla4<tm1All>,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0008078I129S1Sv129X1SvJC57BL6SJLCtla4tm1AllCtla4tm1AllTgTcrAND53Hed0Ctla4tm1AllTgTcrAND53Hed
• premature death_Ctla4<tm1All>/Ctla4<tm1All>,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJC57BL6SJLCtla4tm1AllCtla4tm1AllTgTcrAND53Hed0Ctla4tm1AllTgTcrAND53Hed
• abnormal T cell subpopulation ratio_Ctla4<tm1All>/Ctla4<tm1All>,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0003944I129S1Sv129X1SvJC57BL6SJLCtla4tm1AllCtla4tm1AllTgTcrAND53Hed0Ctla4tm1AllTgTcrAND53Hed
• abnormal lymphopoiesis_Ctla4<tm1All>/Ctla4<tm1All>,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0002401I129S1Sv129X1SvJC57BL6SJLCtla4tm1AllCtla4tm1AllTgTcrAND53Hed0Ctla4tm1AllTgTcrAND53Hed
• abnormal T cell activation_Ctla4<tm1All>/Ctla4<tm1All>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0001828I129SSv129X1SvJC57BL6SJLCtla4tm1AllCtla4tm1AllRag1tm1MomRag1tm1MomTgTcrAND53Hed0TgTcrAND53HedRag1tm1MomCtla4tm1All