F. Tronche, et.al., Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety., Nature genetics, 1999, 23

http://rdf.ncbi.nlm.nih.gov/pubmed/10471508

F. Tronche, et.al., Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety., Nature genetics, 1999, 23

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Nes-cre)1Kln
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176173
• Nr3c1<tm2Gsc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1931327

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Nes-cre)1Kln
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176173
• Nr3c1<tm2Gsc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1931327

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased anxiety-related response_Nr3c1<tm2Gsc>/Nr3c1<tm2Gsc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001364I129P2OlaHsdC57BL6JSJLNr3c1tm2GscNr3c1tm2GscTgNescre1Kln0Nr3c1tm2GscTgNescre1Kln
• decreased body size_Nr3c1<tm2Gsc>/Nr3c1<tm2Gsc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001265I129P2OlaHsdC57BL6JSJLNr3c1tm2GscNr3c1tm2GscTgNescre1Kln0Nr3c1tm2GscTgNescre1Kln
• abnormal fear/anxiety-related behavior_Nr3c1<tm2Gsc>/Nr3c1<tm2Gsc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002065I129P2OlaHsdC57BL6JSJLNr3c1tm2GscNr3c1tm2GscTgNescre1Kln0Nr3c1tm2GscTgNescre1Kln
• decreased circulating adrenocorticotropin level_Nr3c1<tm2Gsc>/Nr3c1<tm2Gsc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002664I129P2OlaHsdC57BL6JSJLNr3c1tm2GscNr3c1tm2GscTgNescre1Kln0Nr3c1tm2GscTgNescre1Kln
• decreased body weight_Nr3c1<tm2Gsc>/Nr3c1<tm2Gsc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001262I129P2OlaHsdC57BL6JSJLNr3c1tm2GscNr3c1tm2GscTgNescre1Kln0Nr3c1tm2GscTgNescre1Kln
• abnormal adipose tissue distribution_Nr3c1<tm2Gsc>/Nr3c1<tm2Gsc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000013I129P2OlaHsdC57BL6JSJLNr3c1tm2GscNr3c1tm2GscTgNescre1Kln0Nr3c1tm2GscTgNescre1Kln
• decreased bone mineral density_Nr3c1<tm2Gsc>/Nr3c1<tm2Gsc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000063I129P2OlaHsdC57BL6JSJLNr3c1tm2GscNr3c1tm2GscTgNescre1Kln0Nr3c1tm2GscTgNescre1Kln
• osteoporosis_Nr3c1<tm2Gsc>/Nr3c1<tm2Gsc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000066I129P2OlaHsdC57BL6JSJLNr3c1tm2GscNr3c1tm2GscTgNescre1Kln0Nr3c1tm2GscTgNescre1Kln
• decreased body length_Nr3c1<tm2Gsc>/Nr3c1<tm2Gsc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001258I129P2OlaHsdC57BL6JSJLNr3c1tm2GscNr3c1tm2GscTgNescre1Kln0Nr3c1tm2GscTgNescre1Kln
• hypersecretion of corticotropin-releasing hormone_Nr3c1<tm2Gsc>/Nr3c1<tm2Gsc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001753I129P2OlaHsdC57BL6JSJLNr3c1tm2GscNr3c1tm2GscTgNescre1Kln0Nr3c1tm2GscTgNescre1Kln
• increased circulating glucocorticoid level_Nr3c1<tm2Gsc>/Nr3c1<tm2Gsc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003367I129P2OlaHsdC57BL6JSJLNr3c1tm2GscNr3c1tm2GscTgNescre1Kln0Nr3c1tm2GscTgNescre1Kln
• increased adrenocorticotropin level_Nr3c1<tm2Gsc>/Nr3c1<tm2Gsc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005129I129P2OlaHsdC57BL6JSJLNr3c1tm2GscNr3c1tm2GscTgNescre1Kln0Nr3c1tm2GscTgNescre1Kln