A. Herreman, et.al., Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency., Proceedings of the National Academy of Sciences of the United States of America, 1999, 96

http://rdf.ncbi.nlm.nih.gov/pubmed/10518543

A. Herreman, et.al., Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency., Proceedings of the National Academy of Sciences of the United States of America, 1999, 96

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Psen2<tm1Bdes>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2149117

class

http://purl.org/net/cito/citesAsAuthority

• Psen2<tm1Bdes>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2149117

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• lung hemorrhage_Psen2<tm1Bdes>/Psen2<tm1Bdes>
  http://metadb.riken.jp/0001182I129P2OlaHsdC57BL6JPsen2tm1BdesPsen2tm1BdesPsen2tm1Bdes
• prenatal lethality, complete penetrance_Psen1<tm1Bdes>/Psen1<tm1Bdes>,Psen2<tm1Bdes>/Psen2<tm1Bdes>
  http://metadb.riken.jp/0011091I129P2OlaHsdC57BL6JPsen1tm1BdesPsen1tm1BdesPsen2tm1BdesPsen2tm1BdesPsen1tm1BdesPsen2tm1Bdes
• abnormal brain development_Psen1<tm1Bdes>/Psen1<tm1Bdes>,Psen2<tm1Bdes>/Psen2<tm1Bdes>
  http://metadb.riken.jp/0000913I129P2OlaHsdC57BL6JPsen1tm1BdesPsen1tm1BdesPsen2tm1BdesPsen2tm1BdesPsen1tm1BdesPsen2tm1Bdes
• caudal body truncation_Psen1<tm1Bdes>/Psen1<tm1Bdes>,Psen2<tm1Bdes>/Psen2<tm1Bdes>
  http://metadb.riken.jp/0004073I129P2OlaHsdC57BL6JPsen1tm1BdesPsen1tm1BdesPsen2tm1BdesPsen2tm1BdesPsen1tm1BdesPsen2tm1Bdes
• abnormal forebrain development_Psen1<tm1Bdes>/Psen1<tm1Bdes>,Psen2<tm1Bdes>/Psen2<tm1Bdes>
  http://metadb.riken.jp/0003232I129P2OlaHsdC57BL6JPsen1tm1BdesPsen1tm1BdesPsen2tm1BdesPsen2tm1BdesPsen1tm1BdesPsen2tm1Bdes
• embryonic growth retardation_Psen1<tm1Bdes>/Psen1<tm1Bdes>,Psen2<tm1Bdes>/Psen2<tm1Bdes>
  http://metadb.riken.jp/0003984I129P2OlaHsdC57BL6JPsen1tm1BdesPsen1tm1BdesPsen2tm1BdesPsen2tm1BdesPsen1tm1BdesPsen2tm1Bdes
• abnormal blood circulation_Psen1<tm1Bdes>/Psen1<tm1Bdes>,Psen2<tm1Bdes>/Psen2<tm1Bdes>
  http://metadb.riken.jp/0002128I129P2OlaHsdC57BL6JPsen1tm1BdesPsen1tm1BdesPsen2tm1BdesPsen2tm1BdesPsen1tm1BdesPsen2tm1Bdes
• increased lung endothelial cell apoptosis_Psen2<tm1Bdes>/Psen2<tm1Bdes>
  http://metadb.riken.jp/0011141I129P2OlaHsdC57BL6JPsen2tm1BdesPsen2tm1BdesPsen2tm1Bdes
• abnormal respiratory system physiology_Psen2<tm1Bdes>/Psen2<tm1Bdes>
  http://metadb.riken.jp/0002133I129P2OlaHsdC57BL6JPsen2tm1BdesPsen2tm1BdesPsen2tm1Bdes
• abnormal vitelline vascular remodeling_Psen1<tm1Bdes>/Psen1<tm1Bdes>,Psen2<tm1Bdes>/Psen2<tm1Bdes>
  http://metadb.riken.jp/0004076I129P2OlaHsdC57BL6JPsen1tm1BdesPsen1tm1BdesPsen2tm1BdesPsen2tm1BdesPsen1tm1BdesPsen2tm1Bdes
• abnormal visceral yolk sac morphology_Psen1<tm1Bdes>/Psen1<tm1Bdes>,Psen2<tm1Bdes>/Psen2<tm1Bdes>
  http://metadb.riken.jp/0001718I129P2OlaHsdC57BL6JPsen1tm1BdesPsen1tm1BdesPsen2tm1BdesPsen2tm1BdesPsen1tm1BdesPsen2tm1Bdes
• abnormal hindbrain development_Psen1<tm1Bdes>/Psen1<tm1Bdes>,Psen2<tm1Bdes>/Psen2<tm1Bdes>
  http://metadb.riken.jp/0006108I129P2OlaHsdC57BL6JPsen1tm1BdesPsen1tm1BdesPsen2tm1BdesPsen2tm1BdesPsen1tm1BdesPsen2tm1Bdes
• pulmonary fibrosis_Psen2<tm1Bdes>/Psen2<tm1Bdes>
  http://metadb.riken.jp/0006050I129P2OlaHsdC57BL6JPsen2tm1BdesPsen2tm1BdesPsen2tm1Bdes
• abnormal pulmonary alveolus wall morphology_Psen2<tm1Bdes>/Psen2<tm1Bdes>
  http://metadb.riken.jp/0010903I129P2OlaHsdC57BL6JPsen2tm1BdesPsen2tm1BdesPsen2tm1Bdes
• abnormal vitelline vasculature morphology_Psen1<tm1Bdes>/Psen1<tm1Bdes>,Psen2<tm1Bdes>/Psen2<tm1Bdes>
  http://metadb.riken.jp/0003229I129P2OlaHsdC57BL6JPsen1tm1BdesPsen1tm1BdesPsen2tm1BdesPsen2tm1BdesPsen1tm1BdesPsen2tm1Bdes
• kinked neural tube_Psen1<tm1Bdes>/Psen1<tm1Bdes>,Psen2<tm1Bdes>/Psen2<tm1Bdes>
  http://metadb.riken.jp/0003400I129P2OlaHsdC57BL6JPsen1tm1BdesPsen1tm1BdesPsen2tm1BdesPsen2tm1BdesPsen1tm1BdesPsen2tm1Bdes
• distended pericardium_Psen1<tm1Bdes>/Psen1<tm1Bdes>,Psen2<tm1Bdes>/Psen2<tm1Bdes>
  http://metadb.riken.jp/0000292I129P2OlaHsdC57BL6JPsen1tm1BdesPsen1tm1BdesPsen2tm1BdesPsen2tm1BdesPsen1tm1BdesPsen2tm1Bdes