K. Holmbeck, et.al., MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover., Cell, 1999, 99

http://rdf.ncbi.nlm.nih.gov/pubmed/10520996

K. Holmbeck, et.al., MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover., Cell, 1999, 99

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mmp14<tm1Hbh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2445723

class

http://purl.org/net/cito/citesAsAuthority

• Mmp14<tm1Hbh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2445723

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• focal hair loss_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0000418I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• abnormal parietal bone morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0000109I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• abnormal skeleton development_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0002113I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• abnormal cartilage morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0000163I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• skeletal muscle fibrosis_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0009419I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• lordosis_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0000162I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• hypoactivity_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0001402I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• absent sexual maturation_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0003379I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• kyphosis_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0000160I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• abnormal forelimb morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0000550I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• abnormal chondrocyte morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0000166I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• osteoporosis_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0000066I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• skin fibrosis_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0009932I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• decreased body weight_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0001262I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• cachexia_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0005150I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• abnormal interparietal bone morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0000077I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• decreased bone mineral density_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0000063I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• abnormal skeleton physiology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0001533I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• abnormal cranial suture morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0002835I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• abnormal osteoclast physiology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0001541I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• decreased length of long bones_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0004686I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• abnormal long bone morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0003723I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• decreased body size_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0001265I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• disproportionate dwarf_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0002427I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• abnormal cranium morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0000438I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• abnormal bone ossification_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0008271I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• abnormal fontanelle morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0000084I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• premature death_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0002083I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• postnatal lethality, incomplete penetrance_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0011086I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• abnormal trabecular bone morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0000130I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• abnormal long bone epiphyseal plate morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0003055I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• delayed bone ossification_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0000060I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• abnormal neurocranium morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0000074I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• arthritis_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0002993I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• domed cranium_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0000440I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• short snout_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0000445I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• abnormal orbit morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0010030I129P2OlaHsdBlackSwissMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh