W. Xu, et.al., Multiorgan autonomic dysfunction in mice lacking the beta2 and the beta4 subunits of neuronal nicotinic acetylcholine receptors., The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, 19

http://rdf.ncbi.nlm.nih.gov/pubmed/10531434

W. Xu, et.al., Multiorgan autonomic dysfunction in mice lacking the beta2 and the beta4 subunits of neuronal nicotinic acetylcholine receptors., The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, 19

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Chrnb2<tm1Mdb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2158714
• Chrnb4<tm1Mdb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2158716

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal urinary bladder morphology_Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0000538I129S7SvEvBrdC57BL6JChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1Mdb
• delayed ear emergence_Chrnb2<tm1Mdb>/Chrnb2<tm1Mdb>,Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0000054I129S7SvEvBrdC57BL6JChrnb2tm1MdbChrnb2tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb2tm1Mdb
• narrow eye opening_Chrnb2<tm1Mdb>/Chrnb2<tm1Mdb>,Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0005287I129S7SvEvBrdC57BL6JChrnb2tm1MdbChrnb2tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb2tm1Mdb
• urinary bladder inflammation_Chrnb2<tm1Mdb>/Chrnb2<tm1Mdb>,Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0009646I129S7SvEvBrdC57BL6JChrnb2tm1MdbChrnb2tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb2tm1Mdb
• abnormal autonomic nervous system physiology_Chrnb2<tm1Mdb>/Chrnb2<tm1Mdb>,Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0006276I129S7SvEvBrdC57BL6JChrnb2tm1MdbChrnb2tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb2tm1Mdb
• abnormal urinary bladder physiology_Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0010386I129S7SvEvBrdC57BL6JChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1Mdb
• mydriasis_Chrnb2<tm1Mdb>/Chrnb2<tm1Mdb>,Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0002546I129S7SvEvBrdC57BL6JChrnb2tm1MdbChrnb2tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb2tm1Mdb
• eyelids fail to open_Chrnb2<tm1Mdb>/Chrnb2<tm1Mdb>,Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0005176I129S7SvEvBrdC57BL6JChrnb2tm1MdbChrnb2tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb2tm1Mdb
• delayed hair appearance_Chrnb2<tm1Mdb>/Chrnb2<tm1Mdb>,Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0000422I129S7SvEvBrdC57BL6JChrnb2tm1MdbChrnb2tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb2tm1Mdb
• no abnormal phenotype detected_Chrnb2<tm1Mdb>/Chrnb2<tm1Mdb>
  http://metadb.riken.jp/0002169I129S7SvEvBrdC57BL6JChrnb2tm1MdbChrnb2tm1MdbChrnb2tm1Mdb
• postnatal lethality, complete penetrance_Chrnb2<tm1Mdb>/Chrnb2<tm1Mdb>,Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0011085I129S7SvEvBrdC57BL6JChrnb2tm1MdbChrnb2tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb2tm1Mdb
• abnormal single cell response_Chrnb2<tm1Mdb>/Chrnb2<tm1Mdb>,Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0003463I129S7SvEvBrdC57BL6JChrnb2tm1MdbChrnb2tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb2tm1Mdb
• impaired pupillary reflex_Chrnb2<tm1Mdb>/Chrnb2<tm1Mdb>,Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0006243I129S7SvEvBrdC57BL6JChrnb2tm1MdbChrnb2tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb2tm1Mdb
• cystolithiasis_Chrnb2<tm1Mdb>/Chrnb2<tm1Mdb>,Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0011625I129S7SvEvBrdC57BL6JChrnb2tm1MdbChrnb2tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb2tm1Mdb
• distended urinary bladder_Chrnb2<tm1Mdb>/Chrnb2<tm1Mdb>,Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0000539I129S7SvEvBrdC57BL6JChrnb2tm1MdbChrnb2tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb2tm1Mdb
• intestinal hypoperistalsis_Chrnb2<tm1Mdb>/Chrnb2<tm1Mdb>,Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0003290I129S7SvEvBrdC57BL6JChrnb2tm1MdbChrnb2tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb2tm1Mdb
• abnormal urinary bladder physiology_Chrnb2<tm1Mdb>/Chrnb2<tm1Mdb>,Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0010386I129S7SvEvBrdC57BL6JChrnb2tm1MdbChrnb2tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb2tm1Mdb
• increased susceptibility to bacterial infection_Chrnb2<tm1Mdb>/Chrnb2<tm1Mdb>,Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0002412I129S7SvEvBrdC57BL6JChrnb2tm1MdbChrnb2tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb2tm1Mdb
• urinary incontinence_Chrnb2<tm1Mdb>/Chrnb2<tm1Mdb>,Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0003280I129S7SvEvBrdC57BL6JChrnb2tm1MdbChrnb2tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb2tm1Mdb
• abnormal urinary bladder urothelium morphology_Chrnb2<tm1Mdb>/Chrnb2<tm1Mdb>,Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0000540I129S7SvEvBrdC57BL6JChrnb2tm1MdbChrnb2tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb2tm1Mdb
• postnatal growth retardation_Chrnb2<tm1Mdb>/Chrnb2<tm1Mdb>,Chrnb4<tm1Mdb>/Chrnb4<tm1Mdb>
  http://metadb.riken.jp/0001732I129S7SvEvBrdC57BL6JChrnb2tm1MdbChrnb2tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb4tm1MdbChrnb2tm1Mdb

class

http://purl.org/net/cito/citesAsAuthority

• Chrnb2<tm1Mdb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2158714
• Chrnb4<tm1Mdb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2158716

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD45140
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD45140