T. Ishihara, et.al., Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform., Neuron, 1999, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/10595524

T. Ishihara, et.al., Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform., Neuron, 1999, 24

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Prnp-MAPT)7Vle
  http://metadb.riken.jp/db/mgi_rdf/MGI:2385580
• Tg(Prnp-MAPT)43Vle
  http://metadb.riken.jp/db/mgi_rdf/MGI:2385566

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Prnp-MAPT)7Vle
  http://metadb.riken.jp/db/mgi_rdf/MGI:2385580
• Tg(Prnp-MAPT)43Vle
  http://metadb.riken.jp/db/mgi_rdf/MGI:2385566

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased body weight_Tg(Prnp-MAPT)7Vle/0
  http://metadb.riken.jp/0001262IC57BL6SJLTgPrnpMAPT7Vle0TgPrnpMAPT7Vle
• tau protein deposits_Tg(Prnp-MAPT)7Vle/0
  http://metadb.riken.jp/0004250IC57BL6SJLTgPrnpMAPT7Vle0TgPrnpMAPT7Vle
• limb grasping_Tg(Prnp-MAPT)7Vle/0
  http://metadb.riken.jp/0001513IC57BL6SJLTgPrnpMAPT7Vle0TgPrnpMAPT7Vle
• motor neuron degeneration_Tg(Prnp-MAPT)7Vle/0
  http://metadb.riken.jp/0000938IC57BL6SJLTgPrnpMAPT7Vle0TgPrnpMAPT7Vle
• impaired balance_Tg(Prnp-MAPT)43Vle/0
  http://metadb.riken.jp/0001525IC57BL6DBA2TgPrnpMAPT43Vle0TgPrnpMAPT43Vle
• axon degeneration_Tg(Prnp-MAPT)7Vle/0
  http://metadb.riken.jp/0005405IC57BL6SJLTgPrnpMAPT7Vle0TgPrnpMAPT7Vle
• abnormal motor neuron morphology_Tg(Prnp-MAPT)43Vle/0
  http://metadb.riken.jp/0000937IC57BL6DBA2TgPrnpMAPT43Vle0TgPrnpMAPT43Vle
• impaired balance_Tg(Prnp-MAPT)7Vle/0
  http://metadb.riken.jp/0001525IC57BL6SJLTgPrnpMAPT7Vle0TgPrnpMAPT7Vle
• limb grasping_Tg(Prnp-MAPT)43Vle/0
  http://metadb.riken.jp/0001513IC57BL6DBA2TgPrnpMAPT43Vle0TgPrnpMAPT43Vle
• abnormal motor neuron morphology_Tg(Prnp-MAPT)7Vle/0
  http://metadb.riken.jp/0000937IC57BL6SJLTgPrnpMAPT7Vle0TgPrnpMAPT7Vle
• motor neuron degeneration_Tg(Prnp-MAPT)43Vle/0
  http://metadb.riken.jp/0000938IC57BL6DBA2TgPrnpMAPT43Vle0TgPrnpMAPT43Vle
• abnormal axonal transport_Tg(Prnp-MAPT)43Vle/0
  http://metadb.riken.jp/0004768IC57BL6DBA2TgPrnpMAPT43Vle0TgPrnpMAPT43Vle
• abnormal axon morphology_Tg(Prnp-MAPT)43Vle/0
  http://metadb.riken.jp/0005404IC57BL6DBA2TgPrnpMAPT43Vle0TgPrnpMAPT43Vle
• weakness_Tg(Prnp-MAPT)7Vle/0
  http://metadb.riken.jp/0000746IC57BL6SJLTgPrnpMAPT7Vle0TgPrnpMAPT7Vle
• astrocytosis_Tg(Prnp-MAPT)7Vle/0
  http://metadb.riken.jp/0003354IC57BL6SJLTgPrnpMAPT7Vle0TgPrnpMAPT7Vle
• abnormal axonal transport_Tg(Prnp-MAPT)7Vle/0
  http://metadb.riken.jp/0004768IC57BL6SJLTgPrnpMAPT7Vle0TgPrnpMAPT7Vle
• astrocytosis_Tg(Prnp-MAPT)43Vle/0
  http://metadb.riken.jp/0003354IC57BL6DBA2TgPrnpMAPT43Vle0TgPrnpMAPT43Vle
• axon degeneration_Tg(Prnp-MAPT)43Vle/0
  http://metadb.riken.jp/0005405IC57BL6DBA2TgPrnpMAPT43Vle0TgPrnpMAPT43Vle
• neurofibrillary tangles_Tg(Prnp-MAPT)7Vle/0
  http://metadb.riken.jp/0003214IC57BL6SJLTgPrnpMAPT7Vle0TgPrnpMAPT7Vle
• decreased body weight_Tg(Prnp-MAPT)43Vle/0
  http://metadb.riken.jp/0001262IC57BL6DBA2TgPrnpMAPT43Vle0TgPrnpMAPT43Vle
• premature death_Tg(Prnp-MAPT)43Vle/Tg(Prnp-MAPT)43Vle
  http://metadb.riken.jp/0002083IC57BL6DBA2TgPrnpMAPT43VleTgPrnpMAPT43VleTgPrnpMAPT43Vle
• tau protein deposits_Tg(Prnp-MAPT)43Vle/0
  http://metadb.riken.jp/0004250IC57BL6DBA2TgPrnpMAPT43Vle0TgPrnpMAPT43Vle
• abnormal axon morphology_Tg(Prnp-MAPT)7Vle/0
  http://metadb.riken.jp/0005404IC57BL6SJLTgPrnpMAPT7Vle0TgPrnpMAPT7Vle