H M. Hsieh-Li, et.al., A mouse model for spinal muscular atrophy., Nature genetics, 2000, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/10615130

H M. Hsieh-Li, et.al., A mouse model for spinal muscular atrophy., Nature genetics, 2000, 24

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Smn1<tm1Hung>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2383990
• Tg(SMN2)1Hung
  http://metadb.riken.jp/db/mgi_rdf/MGI:2383995
• Tg(SMN2)2Hung
  http://metadb.riken.jp/db/mgi_rdf/MGI:3056903

class

http://purl.org/net/cito/citesAsAuthority

• Smn1<tm1Hung>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2383990
• Tg(SMN2)1Hung
  http://metadb.riken.jp/db/mgi_rdf/MGI:2383995
• Tg(SMN2)2Hung
  http://metadb.riken.jp/db/mgi_rdf/MGI:3056903

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• thick tail_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0000588I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung
• short tail_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0000592I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung
• hindlimb paralysis_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0000755I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung
• abnormal motor neuron morphology_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0000937I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung
• decreased motor neuron number_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0000939I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung
• decreased body weight_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0001262I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung
他15件を見る
• premature death_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0002083I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung
• abnormal tail morphology_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0002111I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung
• abnormal astrocyte morphology_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0002182I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung
• muscular atrophy_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0002269I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung
• chromatolysis_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0002883I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung
• abnormal skeletal muscle fiber morphology_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0003084I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung
• extremity edema_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0003201I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung
• hairless_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0003815I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung
• axon degeneration_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0005405I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung
• increased skeletal muscle fiber size_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0009399I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung
• decreased skeletal muscle fiber diameter_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0009402I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung
• decreased skeletal muscle fiber number_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0009406I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung
• postnatal lethality, incomplete penetrance_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0011086I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung
• embryonic lethality between implantation and somite formation, complete penetrance_Smn1<tm1Hung>/Smn1<tm1Hung>
  http://metadb.riken.jp/0011096I129P2OlaHsdSmn1tm1HungSmn1tm1HungSmn1tm1Hung
• tail necrosis_Smn1<tm1Hung>/Smn1<tm1Hung>,Tg(SMN2)2Hung/Tg(SMN2)2Hung
  http://metadb.riken.jp/0013178I129P2OlaHsdFVBNSmn1tm1HungSmn1tm1HungTgSMN22HungTgSMN22HungTgSMN22HungSmn1tm1Hung