M. Accad, et.al., Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1., The Journal of clinical investigation, 2000, 105

http://rdf.ncbi.nlm.nih.gov/pubmed/10727439

M. Accad, et.al., Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1., The Journal of clinical investigation, 2000, 105

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cholesterol homeostasis_Apoe<tm1Unc>/Apoe<tm1Unc>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0005278I129P2OlaHsd129S4SvJaeC57BL6JApoetm1UncApoetm1UncSoat1tm1FarSoat1tm1FarSoat1tm1FarApoetm1Unc
• xanthoma_Apoe<tm1Unc>/Apoe<tm1Unc>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0003692I129P2OlaHsd129S4SvJaeC57BL6JApoetm1UncApoetm1UncSoat1tm1FarSoat1tm1FarSoat1tm1FarApoetm1Unc
• skin inflammation_Apoe<tm1Unc>/Apoe<tm1Unc>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0004947I129P2OlaHsd129S4SvJaeC57BL6JApoetm1UncApoetm1UncSoat1tm1FarSoat1tm1FarSoat1tm1FarApoetm1Unc
• thick dermal layer_Apoe<tm1Unc>/Apoe<tm1Unc>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0001245I129P2OlaHsd129S4SvJaeC57BL6JApoetm1UncApoetm1UncSoat1tm1FarSoat1tm1FarSoat1tm1FarApoetm1Unc
• skin lesions_Apoe<tm1Unc>/Apoe<tm1Unc>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0001212I129P2OlaHsd129S4SvJaeC57BL6JApoetm1UncApoetm1UncSoat1tm1FarSoat1tm1FarSoat1tm1FarApoetm1Unc
• abnormal cerebellum morphology_Ldlr<tm1Her>/Ldlr<tm1Her>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0000849I129S4SvJae129S7SvEvBrdC57BL6JLdlrtm1HerLdlrtm1HerSoat1tm1FarSoat1tm1FarSoat1tm1FarLdlrtm1Her
• abnormal coat appearance_Apoe<tm1Unc>/Apoe<tm1Unc>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0001510I129P2OlaHsd129S4SvJaeC57BL6JApoetm1UncApoetm1UncSoat1tm1FarSoat1tm1FarSoat1tm1FarApoetm1Unc
• atherosclerotic lesions_Apoe<tm1Unc>/Apoe<tm1Unc>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0005338I129P2OlaHsd129S4SvJaeC57BL6JApoetm1UncApoetm1UncSoat1tm1FarSoat1tm1FarSoat1tm1FarApoetm1Unc
• skin edema_Ldlr<tm1Her>/Ldlr<tm1Her>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0001786I129S4SvJae129S7SvEvBrdC57BL6JLdlrtm1HerLdlrtm1HerSoat1tm1FarSoat1tm1FarSoat1tm1FarLdlrtm1Her
• abnormal dermal layer morphology_Ldlr<tm1Her>/Ldlr<tm1Her>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0001243I129S4SvJae129S7SvEvBrdC57BL6JLdlrtm1HerLdlrtm1HerSoat1tm1FarSoat1tm1FarSoat1tm1FarLdlrtm1Her
• sparse hair_Apoe<tm1Unc>/Apoe<tm1Unc>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0000416I129P2OlaHsd129S4SvJaeC57BL6JApoetm1UncApoetm1UncSoat1tm1FarSoat1tm1FarSoat1tm1FarApoetm1Unc
• xanthoma_Ldlr<tm1Her>/Ldlr<tm1Her>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0003692I129S4SvJae129S7SvEvBrdC57BL6JLdlrtm1HerLdlrtm1HerSoat1tm1FarSoat1tm1FarSoat1tm1FarLdlrtm1Her
• abnormal skin morphology_Apoe<tm1Unc>/Apoe<tm1Unc>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0002060I129P2OlaHsd129S4SvJaeC57BL6JApoetm1UncApoetm1UncSoat1tm1FarSoat1tm1FarSoat1tm1FarApoetm1Unc
• abnormal cholesterol level_Apoe<tm1Unc>/Apoe<tm1Unc>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0003947I129P2OlaHsd129S4SvJaeC57BL6JApoetm1UncApoetm1UncSoat1tm1FarSoat1tm1FarSoat1tm1FarApoetm1Unc
• skin fibrosis_Apoe<tm1Unc>/Apoe<tm1Unc>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0009932I129P2OlaHsd129S4SvJaeC57BL6JApoetm1UncApoetm1UncSoat1tm1FarSoat1tm1FarSoat1tm1FarApoetm1Unc
• skin lesions_Ldlr<tm1Her>/Ldlr<tm1Her>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0001212I129S4SvJae129S7SvEvBrdC57BL6JLdlrtm1HerLdlrtm1HerSoat1tm1FarSoat1tm1FarSoat1tm1FarLdlrtm1Her
• thick skin_Ldlr<tm1Her>/Ldlr<tm1Her>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0001200I129S4SvJae129S7SvEvBrdC57BL6JLdlrtm1HerLdlrtm1HerSoat1tm1FarSoat1tm1FarSoat1tm1FarLdlrtm1Her
• decreased circulating cholesterol level_Ldlr<tm1Her>/Ldlr<tm1Her>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0005179I129S4SvJae129S7SvEvBrdC57BL6JLdlrtm1HerLdlrtm1HerSoat1tm1FarSoat1tm1FarSoat1tm1FarLdlrtm1Her
• atherosclerotic lesions_Ldlr<tm1Her>/Ldlr<tm1Her>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0005338I129S4SvJae129S7SvEvBrdC57BL6JLdlrtm1HerLdlrtm1HerSoat1tm1FarSoat1tm1FarSoat1tm1FarLdlrtm1Her
• decreased circulating cholesterol level_Apoe<tm1Unc>/Apoe<tm1Unc>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0005179I129P2OlaHsd129S4SvJaeC57BL6JApoetm1UncApoetm1UncSoat1tm1FarSoat1tm1FarSoat1tm1FarApoetm1Unc
• decreased circulating VLDL cholesterol level_Apoe<tm1Unc>/Apoe<tm1Unc>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0005146I129P2OlaHsd129S4SvJaeC57BL6JApoetm1UncApoetm1UncSoat1tm1FarSoat1tm1FarSoat1tm1FarApoetm1Unc
• hyperkeratosis_Apoe<tm1Unc>/Apoe<tm1Unc>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0001242I129P2OlaHsd129S4SvJaeC57BL6JApoetm1UncApoetm1UncSoat1tm1FarSoat1tm1FarSoat1tm1FarApoetm1Unc
• abnormal brain morphology_Ldlr<tm1Her>/Ldlr<tm1Her>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0002152I129S4SvJae129S7SvEvBrdC57BL6JLdlrtm1HerLdlrtm1HerSoat1tm1FarSoat1tm1FarSoat1tm1FarLdlrtm1Her
• skin inflammation_Ldlr<tm1Her>/Ldlr<tm1Her>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0004947I129S4SvJae129S7SvEvBrdC57BL6JLdlrtm1HerLdlrtm1HerSoat1tm1FarSoat1tm1FarSoat1tm1FarLdlrtm1Her
• abnormal brain morphology_Apoe<tm1Unc>/Apoe<tm1Unc>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0002152I129P2OlaHsd129S4SvJaeC57BL6JApoetm1UncApoetm1UncSoat1tm1FarSoat1tm1FarSoat1tm1FarApoetm1Unc
• abnormal dermal layer morphology_Apoe<tm1Unc>/Apoe<tm1Unc>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0001243I129P2OlaHsd129S4SvJaeC57BL6JApoetm1UncApoetm1UncSoat1tm1FarSoat1tm1FarSoat1tm1FarApoetm1Unc
• abnormal skin condition_Apoe<tm1Unc>/Apoe<tm1Unc>,Soat1<tm1Far>/Soat1<tm1Far>
  http://metadb.riken.jp/0001191I129P2OlaHsd129S4SvJaeC57BL6JApoetm1UncApoetm1UncSoat1tm1FarSoat1tm1FarSoat1tm1FarApoetm1Unc