J C. Devedjian, et.al., Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes., The Journal of clinical investigation, 2000, 105

http://rdf.ncbi.nlm.nih.gov/pubmed/10727441

J C. Devedjian, et.al., Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes., The Journal of clinical investigation, 2000, 105

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Ins-Igf2)1Fbos
  http://metadb.riken.jp/db/mgi_rdf/MGI:3818739

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased pancreatic beta cell mass_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0009113IC57BL6SJLTgInsIgf21Fbos0TgInsIgf21Fbos
• pancreatic islet hyperplasia_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0005491IC57BL6SJLTgInsIgf21Fbos0TgInsIgf21Fbos
• disorganized pancreatic islets_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0009254IC57BL6C57BLKsJSJLTgInsIgf21Fbos0TgInsIgf21Fbos
• increased insulin secretion_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0003058IC57BL6SJLTgInsIgf21Fbos0TgInsIgf21Fbos
• increased circulating glucose level_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0005559IC57BL6SJLTgInsIgf21Fbos0TgInsIgf21Fbos
• increased circulating free fatty acid level_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0001554IC57BL6SJLTgInsIgf21Fbos0TgInsIgf21Fbos
• increased pancreas weight_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0009108IC57BL6SJLTgInsIgf21Fbos0TgInsIgf21Fbos
• hyperglycemia_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0001559IC57BL6C57BLKsJSJLTgInsIgf21Fbos0TgInsIgf21Fbos
• increased circulating triglyceride level_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0001552IC57BL6C57BLKsJSJLTgInsIgf21Fbos0TgInsIgf21Fbos
• decreased susceptibility to weight gain_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0010182IC57BL6SJLTgInsIgf21Fbos0TgInsIgf21Fbos
• obese_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0001261IC57BL6C57BLKsJSJLTgInsIgf21Fbos0TgInsIgf21Fbos
• hepatic steatosis_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0002628IC57BL6C57BLKsJSJLTgInsIgf21Fbos0TgInsIgf21Fbos
• increased circulating triglyceride level_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0001552IC57BL6SJLTgInsIgf21Fbos0TgInsIgf21Fbos
• increased circulating free fatty acid level_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0001554IC57BL6C57BLKsJSJLTgInsIgf21Fbos0TgInsIgf21Fbos
• hyperglycemia_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0001559IC57BL6SJLTgInsIgf21Fbos0TgInsIgf21Fbos
• abnormal pancreatic beta cell physiology_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0003562IC57BL6SJLTgInsIgf21Fbos0TgInsIgf21Fbos
• insulin resistance_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0005331IC57BL6SJLTgInsIgf21Fbos0TgInsIgf21Fbos
• disorganized pancreatic islets_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0009254IC57BL6SJLTgInsIgf21Fbos0TgInsIgf21Fbos
• increased circulating insulin level_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0002079IC57BL6SJLTgInsIgf21Fbos0TgInsIgf21Fbos
• increased circulating insulin level_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0002079IC57BL6C57BLKsJSJLTgInsIgf21Fbos0TgInsIgf21Fbos
• insulin resistance_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0005331IC57BL6C57BLKsJSJLTgInsIgf21Fbos0TgInsIgf21Fbos
• pancreatic islet hyperplasia_Tg(Ins-Igf2)1Fbos/0
  http://metadb.riken.jp/0005491IC57BL6C57BLKsJSJLTgInsIgf21Fbos0TgInsIgf21Fbos

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Ins-Igf2)1Fbos
  http://metadb.riken.jp/db/mgi_rdf/MGI:3818739