A. Yamamoto, et.al., Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease., Cell, 2000, 101

http://rdf.ncbi.nlm.nih.gov/pubmed/10778856

A. Yamamoto, et.al., Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease., Cell, 2000, 101

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-HTT*94Q,-lacZ)1Rhn
  http://metadb.riken.jp/db/mgi_rdf/MGI:3851440

class

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-HTT*94Q,-lacZ)1Rhn
  http://metadb.riken.jp/db/mgi_rdf/MGI:3851440

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• tremors_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-HTT*94Q,-lacZ)1Rhn/0
  http://metadb.riken.jp/0000745IC57BL6CBATgCamk2atTA1Mmay0TgtetOHTT94QlacZ1Rhn0TgCamk2atTA1MmayTgtetOHTT94QlacZ1Rhn
• decreased brain size_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-HTT*94Q,-lacZ)1Rhn/0
  http://metadb.riken.jp/0000774IC57BL6CBATgCamk2atTA1Mmay0TgtetOHTT94QlacZ1Rhn0TgCamk2atTA1MmayTgtetOHTT94QlacZ1Rhn
• hypoactivity_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-HTT*94Q,-lacZ)1Rhn/0
  http://metadb.riken.jp/0001402IC57BL6CBATgCamk2atTA1Mmay0TgtetOHTT94QlacZ1Rhn0TgCamk2atTA1MmayTgtetOHTT94QlacZ1Rhn
• decreased grooming behavior_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-HTT*94Q,-lacZ)1Rhn/0
  http://metadb.riken.jp/0001442IC57BL6CBATgCamk2atTA1Mmay0TgtetOHTT94QlacZ1Rhn0TgCamk2atTA1MmayTgtetOHTT94QlacZ1Rhn
• limb grasping_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-HTT*94Q,-lacZ)1Rhn/0
  http://metadb.riken.jp/0001513IC57BL6CBATgCamk2atTA1Mmay0TgtetOHTT94QlacZ1Rhn0TgCamk2atTA1MmayTgtetOHTT94QlacZ1Rhn
• premature death_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-HTT*94Q,-lacZ)1Rhn/0
  http://metadb.riken.jp/0002083IC57BL6CBATgCamk2atTA1Mmay0TgtetOHTT94QlacZ1Rhn0TgCamk2atTA1MmayTgtetOHTT94QlacZ1Rhn
他9件を見る
• no abnormal phenotype detected_Tg(tetO-HTT*94Q,-lacZ)1Rhn/0
  http://metadb.riken.jp/0002169IC57BL6CBATgtetOHTT94QlacZ1Rhn0TgtetOHTT94QlacZ1Rhn
• gliosis_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-HTT*94Q,-lacZ)1Rhn/0
  http://metadb.riken.jp/0002183IC57BL6CBATgCamk2atTA1Mmay0TgtetOHTT94QlacZ1Rhn0TgCamk2atTA1MmayTgtetOHTT94QlacZ1Rhn
• astrocytosis_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-HTT*94Q,-lacZ)1Rhn/0
  http://metadb.riken.jp/0003354IC57BL6CBATgCamk2atTA1Mmay0TgtetOHTT94QlacZ1Rhn0TgCamk2atTA1MmayTgtetOHTT94QlacZ1Rhn
• abnormal dorsal striatum morphology_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-HTT*94Q,-lacZ)1Rhn/0
  http://metadb.riken.jp/0004102IC57BL6CBATgCamk2atTA1Mmay0TgtetOHTT94QlacZ1Rhn0TgCamk2atTA1MmayTgtetOHTT94QlacZ1Rhn
• neuronal intranuclear inclusions_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-HTT*94Q,-lacZ)1Rhn/0
  http://metadb.riken.jp/0004191IC57BL6CBATgCamk2atTA1Mmay0TgtetOHTT94QlacZ1Rhn0TgCamk2atTA1MmayTgtetOHTT94QlacZ1Rhn
• dystonia_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-HTT*94Q,-lacZ)1Rhn/0
  http://metadb.riken.jp/0005323IC57BL6CBATgCamk2atTA1Mmay0TgtetOHTT94QlacZ1Rhn0TgCamk2atTA1MmayTgtetOHTT94QlacZ1Rhn
• prenatal lethality, incomplete penetrance_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-HTT*94Q,-lacZ)1Rhn/0
  http://metadb.riken.jp/0011101IC57BL6CBATgCamk2atTA1Mmay0TgtetOHTT94QlacZ1Rhn0TgCamk2atTA1MmayTgtetOHTT94QlacZ1Rhn
• enlarged brain ventricles_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-HTT*94Q,-lacZ)1Rhn/0
  http://metadb.riken.jp/0011380IC57BL6CBATgCamk2atTA1Mmay0TgtetOHTT94QlacZ1Rhn0TgCamk2atTA1MmayTgtetOHTT94QlacZ1Rhn
• decreased striatum area_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-HTT*94Q,-lacZ)1Rhn/0
  http://metadb.riken.jp/0012468IC57BL6CBATgCamk2atTA1Mmay0TgtetOHTT94QlacZ1Rhn0TgCamk2atTA1MmayTgtetOHTT94QlacZ1Rhn