J N. Kew, et.al., Functional consequences of reduction in NMDA receptor glycine affinity in mice carrying targeted point mutations in the glycine binding site., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, 20

http://rdf.ncbi.nlm.nih.gov/pubmed/10818139

J N. Kew, et.al., Functional consequences of reduction in NMDA receptor glycine affinity in mice carrying targeted point mutations in the glycine binding site., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, 20

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Grin1<tm1Blt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1928283
• Grin1<tm2Blt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1928284

class

http://purl.org/net/cito/citesAsAuthority

• Grin1<tm1Blt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1928283
• Grin1<tm2Blt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1928284

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased startle reflex_Grin1<tm1Blt>/Grin1<tm1Blt>
  http://metadb.riken.jp/0001488I129P2OlaHsdC57BL6Grin1tm1BltGrin1tm1BltGrin1tm1Blt
• decreased body weight_Grin1<tm2Blt>/Grin1<tm2Blt>
  http://metadb.riken.jp/0001262I129P2OlaHsdC57BL6Grin1tm2BltGrin1tm2BltGrin1tm2Blt
• decreased susceptibility to pharmacologically induced seizures_Grin1<tm1Blt>/Grin1<tm1Blt>
  http://metadb.riken.jp/0002887I129P2OlaHsdC57BL6Grin1tm1BltGrin1tm1BltGrin1tm1Blt
• no suckling reflex_Grin1<tm2Blt>/Grin1<tm2Blt>
  http://metadb.riken.jp/0001435I129P2OlaHsdC57BL6Grin1tm2BltGrin1tm2BltGrin1tm2Blt
• postnatal growth retardation_Grin1<tm2Blt>/Grin1<tm2Blt>
  http://metadb.riken.jp/0001732I129P2OlaHsdC57BL6Grin1tm2BltGrin1tm2BltGrin1tm2Blt
• abnormal spatial learning_Grin1<tm1Blt>/Grin1<tm1Blt>
  http://metadb.riken.jp/0001463I129P2OlaHsdC57BL6Grin1tm1BltGrin1tm1BltGrin1tm1Blt
• abnormal nervous system physiology_Grin1<tm1Blt>/Grin1<tm1Blt>
  http://metadb.riken.jp/0003633I129P2OlaHsdC57BL6Grin1tm1BltGrin1tm1BltGrin1tm1Blt
• abnormal nervous system physiology_Grin1<tm2Blt>/Grin1<tm2Blt>
  http://metadb.riken.jp/0003633I129P2OlaHsdC57BL6Grin1tm2BltGrin1tm2BltGrin1tm2Blt
• abnormal locomotor behavior_Grin1<tm1Blt>/Grin1<tm1Blt>
  http://metadb.riken.jp/0001392I129P2OlaHsdC57BL6Grin1tm1BltGrin1tm1BltGrin1tm1Blt
• postnatal lethality, complete penetrance_Grin1<tm2Blt>/Grin1<tm2Blt>
  http://metadb.riken.jp/0011085I129P2OlaHsdC57BL6Grin1tm2BltGrin1tm2BltGrin1tm2Blt
• impaired coordination_Grin1<tm1Blt>/Grin1<tm1Blt>
  http://metadb.riken.jp/0001405I129P2OlaHsdC57BL6Grin1tm1BltGrin1tm1BltGrin1tm1Blt
• reduced long term potentiation_Grin1<tm1Blt>/Grin1<tm1Blt>
  http://metadb.riken.jp/0001473I129P2OlaHsdC57BL6Grin1tm1BltGrin1tm1BltGrin1tm1Blt