E. Arpaia, et.al., Mitochondrial basis for immune deficiency. Evidence from purine nucleoside phosphorylase-deficient mice., The Journal of experimental medicine, 2000, 191

http://rdf.ncbi.nlm.nih.gov/pubmed/10859343

E. Arpaia, et.al., Mitochondrial basis for immune deficiency. Evidence from purine nucleoside phosphorylase-deficient mice., The Journal of experimental medicine, 2000, 191

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pnp<tm1Cmr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2386195

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased purine-nucleoside phosphorylase activity_Pnp<tm1Cmr>/Pnp<tm1Cmr>
  http://metadb.riken.jp/0011597I129Pnptm1CmrPnptm1CmrPnptm1Cmr
• decreased double-positive T cell number_Pnp<tm1Cmr>/Pnp<tm1Cmr>
  http://metadb.riken.jp/0005092I129Pnptm1CmrPnptm1CmrPnptm1Cmr
• increased cellular sensitivity to gamma-irradiation_Pnp<tm1Cmr>/Pnp<tm1Cmr>
  http://metadb.riken.jp/0002007I129Pnptm1CmrPnptm1CmrPnptm1Cmr
• abnormal urine nucleoside level_Pnp<tm1Cmr>/Pnp<tm1Cmr>
  http://metadb.riken.jp/0011477I129Pnptm1CmrPnptm1CmrPnptm1Cmr
• decreased CD8-positive, alpha-beta T cell number_Pnp<tm1Cmr>/Pnp<tm1Cmr>
  http://metadb.riken.jp/0008079I129Pnptm1CmrPnptm1CmrPnptm1Cmr
• abnormal myelopoiesis_Pnp<tm1Cmr>/Pnp<tm1Cmr>
  http://metadb.riken.jp/0001601I129Pnptm1CmrPnptm1CmrPnptm1Cmr
• increased pre-B cell number_Pnp<tm1Cmr>/Pnp<tm1Cmr>
  http://metadb.riken.jp/0003132I129Pnptm1CmrPnptm1CmrPnptm1Cmr
• decreased CD4-positive, alpha beta T cell number_Pnp<tm1Cmr>/Pnp<tm1Cmr>
  http://metadb.riken.jp/0008075I129Pnptm1CmrPnptm1CmrPnptm1Cmr
• increased thymocyte apoptosis_Pnp<tm1Cmr>/Pnp<tm1Cmr>
  http://metadb.riken.jp/0009541I129Pnptm1CmrPnptm1CmrPnptm1Cmr
• abnormal enzyme/coenzyme activity_Pnp<tm1Cmr>/Pnp<tm1Cmr>
  http://metadb.riken.jp/0005584I129Pnptm1CmrPnptm1CmrPnptm1Cmr
• abnormal mitochondrial physiology_Pnp<tm1Cmr>/Pnp<tm1Cmr>
  http://metadb.riken.jp/0006036I129Pnptm1CmrPnptm1CmrPnptm1Cmr
• decreased single-positive T cell number_Pnp<tm1Cmr>/Pnp<tm1Cmr>
  http://metadb.riken.jp/0008083I129Pnptm1CmrPnptm1CmrPnptm1Cmr
• decreased cytotoxic T cell cytolysis_Pnp<tm1Cmr>/Pnp<tm1Cmr>
  http://metadb.riken.jp/0005079I129Pnptm1CmrPnptm1CmrPnptm1Cmr
• abnormal DNA repair_Pnp<tm1Cmr>/Pnp<tm1Cmr>
  http://metadb.riken.jp/0008058I129Pnptm1CmrPnptm1CmrPnptm1Cmr
• increased double-negative T cell number_Pnp<tm1Cmr>/Pnp<tm1Cmr>
  http://metadb.riken.jp/0005090I129Pnptm1CmrPnptm1CmrPnptm1Cmr

class

http://purl.org/net/cito/citesAsAuthority

• Pnp<tm1Cmr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2386195