R J. Barndt, et.al., Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB., Molecular and cellular biology, 2000, 20

http://rdf.ncbi.nlm.nih.gov/pubmed/10958665

R J. Barndt, et.al., Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB., Molecular and cellular biology, 2000, 20

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tcf12<tm2Zhu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3707160

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased thymocyte number_Tcf12<tm1Zhu>/Tcf12<tm1Zhu>
  http://metadb.riken.jp/0000715I129S7SvEvBrdTcf12tm1ZhuTcf12tm1ZhuTcf12tm1Zhu
• decreased immature B cell number_Tcf12<tm2Zhu>/Tcf12<tm2Zhu>
  http://metadb.riken.jp/0008215NSTcf12tm2ZhuTcf12tm2ZhuTcf12tm2Zhu
• abnormal B cell differentiation_Tcf12<tm2Zhu>/Tcf12<tm2Zhu>
  http://metadb.riken.jp/0002144NSTcf12tm2ZhuTcf12tm2ZhuTcf12tm2Zhu
• absent T cells_Tcf12<tm2Zhu>/Tcf12<tm2Zhu>
  http://metadb.riken.jp/0008070NSTcf12tm2ZhuTcf12tm2ZhuTcf12tm2Zhu
• seizures_Tcf12<tm2Zhu>/Tcf12<+>
  http://metadb.riken.jp/0002064NSTcf12tm2ZhuTcf12Tcf12Tcf12tm2Zhu
• decreased thymocyte number_Tcf12<tm2Zhu>/Tcf12<tm2Zhu>
  http://metadb.riken.jp/0000715NSTcf12tm2ZhuTcf12tm2ZhuTcf12tm2Zhu
• arrested T cell differentiation_Tcf12<tm2Zhu>/Tcf12<tm2Zhu>
  http://metadb.riken.jp/0001825NSTcf12tm2ZhuTcf12tm2ZhuTcf12tm2Zhu
• arrested T cell differentiation_Tcf12<tm2Zhu>/Tcf12<tm2Zhu>,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0001825IC57BL6SJLTcf12tm2ZhuTcf12tm2ZhuTgTcrAND53Hed0Tcf12tm2ZhuTgTcrAND53Hed
• increased T cell number_Tcf12<tm2Zhu>/Tcf12<tm2Zhu>,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0005015IC57BL6SJLTcf12tm2ZhuTcf12tm2ZhuTgTcrAND53Hed0Tcf12tm2ZhuTgTcrAND53Hed
• abnormal CD4-positive, alpha beta T cell morphology_Tcf12<tm2Zhu>/Tcf12<tm2Zhu>,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0002432IC57BL6SJLTcf12tm2ZhuTcf12tm2ZhuTgTcrAND53Hed0Tcf12tm2ZhuTgTcrAND53Hed
• thymus hypoplasia_Tcf12<tm2Zhu>/Tcf12<tm2Zhu>
  http://metadb.riken.jp/0001823NSTcf12tm2ZhuTcf12tm2ZhuTcf12tm2Zhu
• postnatal lethality, incomplete penetrance_Tcf12<tm2Zhu>/Tcf12<tm2Zhu>
  http://metadb.riken.jp/0011086NSTcf12tm2ZhuTcf12tm2ZhuTcf12tm2Zhu
• arrested T cell differentiation_Tcf12<tm1Zhu>/Tcf12<tm2Zhu>
  http://metadb.riken.jp/0001825I129S7SvEvBrdTcf12tm1ZhuTcf12tm2ZhuTcf12tm1ZhuTcf12tm2Zhu
• abnormal response to transplant_Tcf12<tm2Zhu>/Tcf12<tm2Zhu>
  http://metadb.riken.jp/0005671NSTcf12tm2ZhuTcf12tm2ZhuTcf12tm2Zhu
• abnormal T cell differentiation_Tcf12<tm2Zhu>/Tcf12<tm2Zhu>
  http://metadb.riken.jp/0002145NSTcf12tm2ZhuTcf12tm2ZhuTcf12tm2Zhu
• increased double-negative T cell number_Tcf12<tm2Zhu>/Tcf12<tm2Zhu>
  http://metadb.riken.jp/0005090NSTcf12tm2ZhuTcf12tm2ZhuTcf12tm2Zhu
• postnatal growth retardation_Tcf12<tm2Zhu>/Tcf12<tm2Zhu>
  http://metadb.riken.jp/0001732NSTcf12tm2ZhuTcf12tm2ZhuTcf12tm2Zhu
• exencephaly_Tcf12<tm2Zhu>/Tcf12<tm2Zhu>
  http://metadb.riken.jp/0000914NSTcf12tm2ZhuTcf12tm2ZhuTcf12tm2Zhu
• decreased pre-B cell number_Tcf12<tm2Zhu>/Tcf12<tm2Zhu>
  http://metadb.riken.jp/0008209NSTcf12tm2ZhuTcf12tm2ZhuTcf12tm2Zhu
• abnormal T cell subpopulation ratio_Tcf12<tm2Zhu>/Tcf12<tm2Zhu>,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0003944IC57BL6SJLTcf12tm2ZhuTcf12tm2ZhuTgTcrAND53Hed0Tcf12tm2ZhuTgTcrAND53Hed
• decreased pro-B cell number_Tcf12<tm2Zhu>/Tcf12<tm2Zhu>
  http://metadb.riken.jp/0008208NSTcf12tm2ZhuTcf12tm2ZhuTcf12tm2Zhu
• arrested T cell differentiation_Tcf12<tm1Zhu>/Tcf12<tm1Zhu>
  http://metadb.riken.jp/0001825I129S7SvEvBrdTcf12tm1ZhuTcf12tm1ZhuTcf12tm1Zhu
• decreased double-positive T cell number_Tcf12<tm2Zhu>/Tcf12<tm2Zhu>
  http://metadb.riken.jp/0005092NSTcf12tm2ZhuTcf12tm2ZhuTcf12tm2Zhu

class

http://purl.org/net/cito/citesAsAuthority

• Tcf12<tm2Zhu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3707160