S. Dupont, et.al., Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes., Development (Cambridge, England), 2000, 127

http://rdf.ncbi.nlm.nih.gov/pubmed/10976058

S. Dupont, et.al., Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes., Development (Cambridge, England), 2000, 127

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Esr1<tm1.1Mma>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2386760
• Esr2<tm1Mma>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2386761
• Esr1<tm1Mma>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2386759
• Esr1<tm1.2Mma>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3775510

class

http://purl.org/net/cito/citesAsAuthority

• Esr1<tm1.1Mma>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2386760
• Esr2<tm1Mma>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2386761
• Esr1<tm1Mma>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2386759
• Esr1<tm1.2Mma>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3775510

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased male germ cell number_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>
  http://metadb.riken.jp/0004901I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr1tm11Mma
• abnormal ovarian folliculogenesis_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>
  http://metadb.riken.jp/0001130I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr1tm11Mma
• vagina hypoplasia_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>
  http://metadb.riken.jp/0008984I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr1tm11Mma
• ovary cysts_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>,Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0002016I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr2tm1MmaEsr2tm1MmaEsr2tm1MmaEsr1tm11Mma
• vagina hypoplasia_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>,Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0008984I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr2tm1MmaEsr2tm1MmaEsr2tm1MmaEsr1tm11Mma
• abnormal seminiferous tubule morphology_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>,Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0002216I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr2tm1MmaEsr2tm1MmaEsr2tm1MmaEsr1tm11Mma
• absent corpus luteum_Esr1<tm1.1Mma>/Esr1<+>,Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0001134I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1Esr2tm1MmaEsr2tm1MmaEsr1Esr1tm11MmaEsr2tm1Mma
• uterus hypoplasia_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>
  http://metadb.riken.jp/0001121I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr1tm11Mma
• female infertility_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>
  http://metadb.riken.jp/0001926I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr1tm11Mma
• reduced female fertility_Esr1<tm1.1Mma>/Esr1<+>,Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0001923I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1Esr2tm1MmaEsr2tm1MmaEsr1Esr1tm11MmaEsr2tm1Mma
• impaired granulosa cell differentiation_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>,Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0003357I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr2tm1MmaEsr2tm1MmaEsr2tm1MmaEsr1tm11Mma
• abnormal response/metabolism to endogenous compounds_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>,Esr2<tm1Mma>/Esr2<+>
  http://metadb.riken.jp/0003638I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr2tm1MmaEsr2Esr2Esr2tm1MmaEsr1tm11Mma
• abnormal ovarian follicle morphology_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>,Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0001131I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr2tm1MmaEsr2tm1MmaEsr2tm1MmaEsr1tm11Mma
• abnormal ovarian follicle morphology_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>
  http://metadb.riken.jp/0001131I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr1tm11Mma
• uterus hypoplasia_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>,Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0001121I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr2tm1MmaEsr2tm1MmaEsr2tm1MmaEsr1tm11Mma
• ovary cysts_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>
  http://metadb.riken.jp/0002016I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr1tm11Mma
• abnormal rete testis morphology_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>
  http://metadb.riken.jp/0006416I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr1tm11Mma
• decreased corpora lutea number_Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0002680I129S2SvPasEsr2tm1MmaEsr2tm1MmaEsr2tm1Mma
• abnormal response/metabolism to endogenous compounds_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>
  http://metadb.riken.jp/0003638I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr1tm11Mma
• abnormal ovary morphology_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>,Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0001126I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr2tm1MmaEsr2tm1MmaEsr2tm1MmaEsr1tm11Mma
• small vagina_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>,Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0008983I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr2tm1MmaEsr2tm1MmaEsr2tm1MmaEsr1tm11Mma
• abnormal response/metabolism to endogenous compounds_Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0003638I129S2SvPasEsr2tm1MmaEsr2tm1MmaEsr2tm1Mma
• abnormal response/metabolism to endogenous compounds_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>,Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0003638I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr2tm1MmaEsr2tm1MmaEsr2tm1MmaEsr1tm11Mma
• abnormal response/metabolism to endogenous compounds_Esr1<tm1.1Mma>/Esr1<+>,Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0003638I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1Esr2tm1MmaEsr2tm1MmaEsr1Esr1tm11MmaEsr2tm1Mma
• thin uterus_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>,Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0009081I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr2tm1MmaEsr2tm1MmaEsr2tm1MmaEsr1tm11Mma
• reduced female fertility_Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0001923I129S2SvPasEsr2tm1MmaEsr2tm1MmaEsr2tm1Mma
• abnormal seminiferous tubule morphology_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>
  http://metadb.riken.jp/0002216I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr1tm11Mma
• abnormal rete testis morphology_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>,Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0006416I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr2tm1MmaEsr2tm1MmaEsr2tm1MmaEsr1tm11Mma
• abnormal secondary ovarian follicle morphology_Esr1<tm1.1Mma>/Esr1<+>,Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0009363I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1Esr2tm1MmaEsr2tm1MmaEsr1Esr1tm11MmaEsr2tm1Mma
• male infertility_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>,Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0001925I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr2tm1MmaEsr2tm1MmaEsr2tm1MmaEsr1tm11Mma
• decreased male germ cell number_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>,Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0004901I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr2tm1MmaEsr2tm1MmaEsr2tm1MmaEsr1tm11Mma
• absent estrous cycle_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>
  http://metadb.riken.jp/0009009I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr1tm11Mma
• abnormal ovary morphology_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>
  http://metadb.riken.jp/0001126I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr1tm11Mma
• absent corpus luteum_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>
  http://metadb.riken.jp/0001134I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr1tm11Mma
• impaired granulosa cell differentiation_Esr1<tm1.1Mma>/Esr1<+>,Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0003357I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1Esr2tm1MmaEsr2tm1MmaEsr1Esr1tm11MmaEsr2tm1Mma
• abnormal Sertoli cell morphology_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>,Esr2<tm1Mma>/Esr2<tm1Mma>
  http://metadb.riken.jp/0002784I129S2SvPasC57BL6SJLEsr1tm11MmaEsr1tm11MmaEsr2tm1MmaEsr2tm1MmaEsr2tm1MmaEsr1tm11Mma