J C. Brüning, et.al., Role of brain insulin receptor in control of body weight and reproduction., Science (New York, N.Y.), 2000, 289

http://rdf.ncbi.nlm.nih.gov/pubmed/11000114

J C. Brüning, et.al., Role of brain insulin receptor in control of body weight and reproduction., Science (New York, N.Y.), 2000, 289

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased white adipose tissue amount_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000008I129S4SvJaeC57BL6JSJLInsrtm1KhnInsrtm1KhnTgNescre1Kln0Insrtm1KhnTgNescre1Kln
• increased body weight_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001260I129S4SvJaeC57BL6JSJLInsrtm1KhnInsrtm1KhnTgNescre1Kln0Insrtm1KhnTgNescre1Kln
• increased circulating leptin level_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005669I129S4SvJaeC57BL6JSJLInsrtm1KhnInsrtm1KhnTgNescre1Kln0Insrtm1KhnTgNescre1Kln
• oligozoospermia_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002687I129S4SvJaeC57BL6JSJLInsrtm1KhnInsrtm1KhnTgNescre1Kln0Insrtm1KhnTgNescre1Kln
• increased circulating insulin level_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002079I129S4SvJaeC57BL6JSJLInsrtm1KhnInsrtm1KhnTgNescre1Kln0Insrtm1KhnTgNescre1Kln
• polyphagia_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001433I129S4SvJaeC57BL6JSJLInsrtm1KhnInsrtm1KhnTgNescre1Kln0Insrtm1KhnTgNescre1Kln
• decreased corpora lutea number_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002680I129S4SvJaeC57BL6JSJLInsrtm1KhnInsrtm1KhnTgNescre1Kln0Insrtm1KhnTgNescre1Kln
• reduced male fertility_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001922I129S4SvJaeC57BL6JSJLInsrtm1KhnInsrtm1KhnTgNescre1Kln0Insrtm1KhnTgNescre1Kln
• insulin resistance_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005331I129S4SvJaeC57BL6JSJLInsrtm1KhnInsrtm1KhnTgNescre1Kln0Insrtm1KhnTgNescre1Kln
• abnormal seminiferous tubule morphology_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002216I129S4SvJaeC57BL6JSJLInsrtm1KhnInsrtm1KhnTgNescre1Kln0Insrtm1KhnTgNescre1Kln
• impaired ovarian folliculogenesis_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001129I129S4SvJaeC57BL6JSJLInsrtm1KhnInsrtm1KhnTgNescre1Kln0Insrtm1KhnTgNescre1Kln
• Leydig cell hypoplasia_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005536I129S4SvJaeC57BL6JSJLInsrtm1KhnInsrtm1KhnTgNescre1Kln0Insrtm1KhnTgNescre1Kln
• decreased circulating luteinizing hormone level_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002773I129S4SvJaeC57BL6JSJLInsrtm1KhnInsrtm1KhnTgNescre1Kln0Insrtm1KhnTgNescre1Kln
• abnormal spermatogenesis_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001156I129S4SvJaeC57BL6JSJLInsrtm1KhnInsrtm1KhnTgNescre1Kln0Insrtm1KhnTgNescre1Kln
• increased circulating triglyceride level_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001552I129S4SvJaeC57BL6JSJLInsrtm1KhnInsrtm1KhnTgNescre1Kln0Insrtm1KhnTgNescre1Kln