J J. Repa, et.al., Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding., The Journal of biological chemistry, 2000, 275

http://rdf.ncbi.nlm.nih.gov/pubmed/11001949

J J. Repa, et.al., Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding., The Journal of biological chemistry, 2000, 275

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased brain weight_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0002175I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• increased circulating cholesterol level_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0005178I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• increased circulating VLDL triglyceride level_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0003975I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• abnormal bile salt homeostasis_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0005365I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• abnormal bile composition_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0004773I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• increased liver weight_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0002981I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• increased sterol level_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0012226I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• increased liver triglyceride level_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0009355I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• increased circulating triglyceride level_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0001552I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• increased cholesterol level_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0003982I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• decreased intestinal cholesterol absorption_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0002647I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• enlarged adrenocortical cells_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0000646I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• abnormal feces composition_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0003868I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• decreased cholesterol level_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0003983I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• increased adrenal gland weight_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0013307I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• enlarged adrenal glands_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0000642I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• enlarged liver_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0000599I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• decreased bile salt level_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0012338I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• increased circulating VLDL cholesterol level_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0005145I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• increased fatty acid level_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0005281I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt
• decreased kidney weight_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>
  http://metadb.riken.jp/0003918I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt