D J. Burks, et.al., IRS-2 pathways integrate female reproduction and energy homeostasis., Nature, 2000, 407

http://rdf.ncbi.nlm.nih.gov/pubmed/11014193

D J. Burks, et.al., IRS-2 pathways integrate female reproduction and energy homeostasis., Nature, 2000, 407

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• obese_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0001261I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• anovulation_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0008869I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• abnormal ovarian follicle morphology_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0001131I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• abnormal oogenesis_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0001931I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• impaired ovarian folliculogenesis_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0001129I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• absent estrous cycle_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0009009I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• decreased circulating luteinizing hormone level_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0002773I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• increased circulating leptin level_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0005669I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• small ovary_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0001127I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• abnormal energy homeostasis_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0005448I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• reduced female fertility_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0001923I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• abnormal ovulation_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0001928I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• decreased circulating prolactin level_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0005121I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• increased total body fat amount_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0010024I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• female infertility_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0001926I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• absent corpus luteum_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0001134I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• decreased circulating progesterone level_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0005185I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• decreased circulating testosterone level_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0002780I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• small pituitary gland_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0005361I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• decreased circulating estradiol level_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0005181I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• polyphagia_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0001433I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• abnormal glucose homeostasis_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0002078I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• decreased gonadotroph cell number_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0008335I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• decreased oocyte number_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0005431I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• reduced male fertility_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0001922I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• abnormal circulating hormone level_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0005418I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• abnormal mating frequency_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0001377I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw
• impaired glucose tolerance_Irs2<tm1Mfw>/Irs2<tm1Mfw>
  http://metadb.riken.jp/0005293I129S1Sv129X1SvJC57BL6JIrs2tm1MfwIrs2tm1MfwIrs2tm1Mfw