G P. Hayhurst, et.al., Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis., Molecular and cellular biology, 2001, 21

http://rdf.ncbi.nlm.nih.gov/pubmed/11158324

G P. Hayhurst, et.al., Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis., Molecular and cellular biology, 2001, 21

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Hnf4a<tm1.1Gonz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2183520
• Hnf4a<tm1Gonz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2183519
• Hnf4a<tm1.2Gonz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2183525

class

http://purl.org/net/cito/citesAsAuthority

• Hnf4a<tm1.1Gonz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2183520
• Hnf4a<tm1Gonz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2183519
• Hnf4a<tm1.2Gonz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2183525

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_Hnf4a<tm1.1Gonz>/Hnf4a<tm1.1Gonz>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0002083I129X1SvJFVBNHnf4atm11GonzHnf4atm11GonzTgAlb1cre1Dlr0TgAlb1cre1DlrHnf4atm11Gonz
• preweaning lethality, complete penetrance_Hnf4a<tm1.2Gonz>/Hnf4a<tm1.2Gonz>
  http://metadb.riken.jp/0011100I129X1SvJFVBNHnf4atm12GonzHnf4atm12GonzHnf4atm12Gonz
• abnormal liver morphology_Hnf4a<tm1.1Gonz>/Hnf4a<tm1.1Gonz>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0000598I129X1SvJFVBNHnf4atm11GonzHnf4atm11GonzTgAlb1cre1Dlr0TgAlb1cre1DlrHnf4atm11Gonz
• preweaning lethality, complete penetrance_Hnf4a<tm1Gonz>/Hnf4a<tm1Gonz>
  http://metadb.riken.jp/0011100I129X1SvJHnf4atm1GonzHnf4atm1GonzHnf4atm1Gonz
• weight loss_Hnf4a<tm1.1Gonz>/Hnf4a<tm1.1Gonz>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0001263I129X1SvJFVBNHnf4atm11GonzHnf4atm11GonzTgAlb1cre1Dlr0TgAlb1cre1DlrHnf4atm11Gonz
• enlarged liver_Hnf4a<tm1.1Gonz>/Hnf4a<tm1.1Gonz>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0000599I129X1SvJFVBNHnf4atm11GonzHnf4atm11GonzTgAlb1cre1Dlr0TgAlb1cre1DlrHnf4atm11Gonz
• decreased circulating HDL cholesterol level_Hnf4a<tm1.1Gonz>/Hnf4a<tm1.1Gonz>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0000186I129X1SvJFVBNHnf4atm11GonzHnf4atm11GonzTgAlb1cre1Dlr0TgAlb1cre1DlrHnf4atm11Gonz
• abnormal hepatocyte morphology_Hnf4a<tm1.1Gonz>/Hnf4a<tm1.1Gonz>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0000607I129X1SvJFVBNHnf4atm11GonzHnf4atm11GonzTgAlb1cre1Dlr0TgAlb1cre1DlrHnf4atm11Gonz
• decreased circulating cholesterol level_Hnf4a<tm1.1Gonz>/Hnf4a<tm1.1Gonz>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0005179I129X1SvJFVBNHnf4atm11GonzHnf4atm11GonzTgAlb1cre1Dlr0TgAlb1cre1DlrHnf4atm11Gonz
• decreased circulating triglyceride level_Hnf4a<tm1.1Gonz>/Hnf4a<tm1.1Gonz>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0002644I129X1SvJFVBNHnf4atm11GonzHnf4atm11GonzTgAlb1cre1Dlr0TgAlb1cre1DlrHnf4atm11Gonz