T. Lindsten, et.al., The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues., Molecular cell, 2000, 6

http://rdf.ncbi.nlm.nih.gov/pubmed/11163212

T. Lindsten, et.al., The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues., Molecular cell, 2000, 6

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Bak1<tm1Thsn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2159364

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• neonatal lethality, incomplete penetrance_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0011088I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• abnormal hearing physiology_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0001963I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• increased leukocyte cell number_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0000218I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• increased neuron number_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0008947I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• enlarged lymph nodes_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0000702I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• decreased physiological sensitivity to xenobiotic_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0008874I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• abnormal splenocyte physiology_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0009333I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• abnormal B cell morphology_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0004939I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• circling_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0001394I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• decreased cellular sensitivity to gamma-irradiation_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0003207I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• no abnormal phenotype detected_Bak1<tm1Thsn>/Bak1<tm1Thsn>
  http://metadb.riken.jp/0002169I129S1Sv129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBak1tm1Thsn
• abnormal definitive hematopoiesis_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0002123I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• abnormal brain morphology_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0002152I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• abnormal T cell morphology_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0008037I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• thrombocytopenia_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0003179I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• anemia_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0001577I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• increased brain size_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0005238I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• enlarged spleen_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0000691I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• increased lymphocyte cell number_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0005013I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• seizures_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0002064I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• interdigital webbing_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0000571I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• increased spleen white pulp amount_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0008478I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• vagina atresia_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0001144I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn
• increased spleen red pulp amount_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm1Sjk>
  http://metadb.riken.jp/0008476I129S1Sv129S1SvImJ129X1SvJC57BL6Bak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm1SjkBaxtm1SjkBak1tm1Thsn

class

http://purl.org/net/cito/citesAsAuthority

• Bak1<tm1Thsn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2159364