D A. Mandelbrot, et.al., B7-dependent T-cell costimulation in mice lacking CD28 and CTLA4., The Journal of clinical investigation, 2001, 107

http://rdf.ncbi.nlm.nih.gov/pubmed/11285307

D A. Mandelbrot, et.al., B7-dependent T-cell costimulation in mice lacking CD28 and CTLA4., The Journal of clinical investigation, 2001, 107

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cd28<tm1Shr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3721239

class

http://purl.org/net/cito/citesAsAuthority

• Cd28<tm1Shr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3721239

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased T cell proliferation_Cd28<tm1Shr>/Cd28<tm1Shr>,Ctla4<tm1Shr>/Ctla4<tm1Shr>
  http://metadb.riken.jp/0005095C129S4Cd28tm1ShrCtla4tm1ShrCd28tm1ShrCd28tm1ShrCtla4tm1ShrCtla4tm1ShrCtla4tm1ShrCd28tm1Shr
• abnormal interferon level_Cd28<tm1Shr>/Cd28<tm1Shr>,Ctla4<tm1Shr>/Ctla4<tm1Shr>
  http://metadb.riken.jp/0008750C129S4Cd28tm1ShrCtla4tm1ShrCd28tm1ShrCd28tm1ShrCtla4tm1ShrCtla4tm1ShrCtla4tm1ShrCd28tm1Shr
• decreased interleukin-2 secretion_Cd28<tm1Shr>/Cd28<tm1Shr>
  http://metadb.riken.jp/0008688I129S4SvJaeBALBcC57BL6Cd28tm1ShrCd28tm1ShrCd28tm1Shr
• abnormal interleukin secretion_Cd28<tm1Shr>/Cd28<tm1Shr>,Ctla4<tm1Shr>/Ctla4<tm1Shr>
  http://metadb.riken.jp/0008568C129S4Cd28tm1ShrCtla4tm1ShrCd28tm1ShrCd28tm1ShrCtla4tm1ShrCtla4tm1ShrCtla4tm1ShrCd28tm1Shr
• decreased CD4-positive, alpha beta T cell number_Cd28<tm1Shr>/Cd28<tm1Shr>
  http://metadb.riken.jp/0008075I129S4SvJaeBALBcC57BL6Cd28tm1ShrCd28tm1ShrCd28tm1Shr
• increased length of allograft survival_Cd28<tm1Shr>/Cd28<tm1Shr>,Ctla4<tm1Shr>/Ctla4<tm1Shr>
  http://metadb.riken.jp/0004751C129S4Cd28tm1ShrCtla4tm1ShrCd28tm1ShrCd28tm1ShrCtla4tm1ShrCtla4tm1ShrCtla4tm1ShrCd28tm1Shr
• decreased T cell proliferation_Cd28<tm1Shr>/Cd28<tm1Shr>
  http://metadb.riken.jp/0005095I129S4SvJaeBALBcC57BL6Cd28tm1ShrCd28tm1ShrCd28tm1Shr
• decreased CD4-positive, alpha beta T cell number_Cd28<tm1Shr>/Cd28<tm1Shr>,Ctla4<tm1Shr>/Ctla4<tm1Shr>
  http://metadb.riken.jp/0008075C129S4Cd28tm1ShrCtla4tm1ShrCd28tm1ShrCd28tm1ShrCtla4tm1ShrCtla4tm1ShrCtla4tm1ShrCd28tm1Shr