J B. Hurov, et.al., Immune system dysfunction and autoimmune disease in mice lacking Emk (Par-1) protein kinase., Molecular and cellular biology, 2001, 21

http://rdf.ncbi.nlm.nih.gov/pubmed/11287624

J B. Hurov, et.al., Immune system dysfunction and autoimmune disease in mice lacking Emk (Par-1) protein kinase., Molecular and cellular biology, 2001, 21

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mark2<tm1Hpw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182819

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• enlarged spleen_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0000691I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• salivary gland inflammation_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0001870I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• increased interleukin-4 secretion_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0008699I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• increased B cell number_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0005014I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• increased interferon-gamma secretion_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0008566I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• increased spleen weight_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0004952I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• increased urine protein level_Mark2<tm1Hpw>/Mark2<+>
  http://metadb.riken.jp/0002962I129X1SvJC57BL6Mark2tm1HpwMark2Mark2Mark2tm1Hpw
• abnormal humoral immune response_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0001800I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• abnormal spleen B cell follicle morphology_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0008470I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• increased renal glomerulus lobularity_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0011567I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• lymph node hyperplasia_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0008102I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• postnatal growth retardation_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0001732I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• postnatal lethality, incomplete penetrance_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0011086I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• increased B cell proliferation_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0005154I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• abnormal CD4-positive, alpha beta T cell morphology_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0002432I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• decreased IgG3 level_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0008498I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• decreased litter size_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0001935I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• hemoglobinuria_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0000315I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• abnormal glomerular capillary morphology_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0011320I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• hemoglobinuria_Mark2<tm1Hpw>/Mark2<+>
  http://metadb.riken.jp/0000315I129X1SvJC57BL6Mark2tm1HpwMark2Mark2Mark2tm1Hpw
• decreased IgM level_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0001806I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• glomerulonephritis_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0002743I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• rectal prolapse_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0000493I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• kidney inflammation_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0001859I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• rectal prolapse_Mark2<tm1Hpw>/Mark2<+>
  http://metadb.riken.jp/0000493I129X1SvJC57BL6Mark2tm1HpwMark2Mark2Mark2tm1Hpw
• enlarged lymph nodes_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0000702I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• mesangial cell hyperplasia_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0011427I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• lung inflammation_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0001861I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• abnormal immune system physiology_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0001790I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• increased urine protein level_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0002962I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• decreased body weight_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0001262I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• decreased B cell proliferation_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0005093I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw
• spleen hyperplasia_Mark2<tm1Hpw>/Mark2<tm1Hpw>
  http://metadb.riken.jp/0000693I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark2tm1Hpw

class

http://purl.org/net/cito/citesAsAuthority

• Mark2<tm1Hpw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182819