F. Zindy, et.al., Control of spermatogenesis in mice by the cyclin D-dependent kinase inhibitors p18(Ink4c) and p19(Ink4d)., Molecular and cellular biology, 2001, 21

http://rdf.ncbi.nlm.nih.gov/pubmed/11287627

F. Zindy, et.al., Control of spermatogenesis in mice by the cyclin D-dependent kinase inhibitors p18(Ink4c) and p19(Ink4d)., Molecular and cellular biology, 2001, 21

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal apoptosis_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>
  http://metadb.riken.jp/0001648I129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2ctm1Bbd
• abnormal spermatogenesis_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>,Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0001156I129P2OlaHsd129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2dtm1MaroCdkn2dtm1MaroCdkn2ctm1BbdCdkn2dtm1Maro
• decreased circulating testosterone level_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>,Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0002780I129P2OlaHsd129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2dtm1MaroCdkn2dtm1MaroCdkn2ctm1BbdCdkn2dtm1Maro
• seminiferous tubule degeneration_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>,Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0001154I129P2OlaHsd129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2dtm1MaroCdkn2dtm1MaroCdkn2ctm1BbdCdkn2dtm1Maro
• increased body weight_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>,Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0001260I129P2OlaHsd129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2dtm1MaroCdkn2dtm1MaroCdkn2ctm1BbdCdkn2dtm1Maro
• abnormal male meiosis_Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0005169I129X1SvJC57BL6Cdkn2dtm1MaroCdkn2dtm1MaroCdkn2dtm1Maro
• Leydig cell hyperplasia_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>
  http://metadb.riken.jp/0001152I129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2ctm1Bbd
• decreased circulating testosterone level_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>
  http://metadb.riken.jp/0002780I129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2ctm1Bbd
• male infertility_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>,Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0001925I129P2OlaHsd129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2dtm1MaroCdkn2dtm1MaroCdkn2ctm1BbdCdkn2dtm1Maro
• abnormal Leydig cell differentiation_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>,Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0013602I129P2OlaHsd129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2dtm1MaroCdkn2dtm1MaroCdkn2ctm1BbdCdkn2dtm1Maro
• oligozoospermia_Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0002687I129X1SvJC57BL6Cdkn2dtm1MaroCdkn2dtm1MaroCdkn2dtm1Maro
• increased pituitary adenoma incidence_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>,Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0002041I129P2OlaHsd129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2dtm1MaroCdkn2dtm1MaroCdkn2ctm1BbdCdkn2dtm1Maro
• abnormal germ cell morphology_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>,Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0002208I129P2OlaHsd129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2dtm1MaroCdkn2dtm1MaroCdkn2ctm1BbdCdkn2dtm1Maro
• abnormal male meiosis_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>,Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0005169I129P2OlaHsd129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2dtm1MaroCdkn2dtm1MaroCdkn2ctm1BbdCdkn2dtm1Maro
• testicular atrophy_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>,Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0003205I129P2OlaHsd129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2dtm1MaroCdkn2dtm1MaroCdkn2ctm1BbdCdkn2dtm1Maro
• Leydig cell hyperplasia_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>,Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0001152I129P2OlaHsd129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2dtm1MaroCdkn2dtm1MaroCdkn2ctm1BbdCdkn2dtm1Maro
• increased pheochromocytoma incidence_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>,Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0002050I129P2OlaHsd129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2dtm1MaroCdkn2dtm1MaroCdkn2ctm1BbdCdkn2dtm1Maro
• increased circulating follicle stimulating hormone level_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>,Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0001750I129P2OlaHsd129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2dtm1MaroCdkn2dtm1MaroCdkn2ctm1BbdCdkn2dtm1Maro
• asthenozoospermia_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>,Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0002675I129P2OlaHsd129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2dtm1MaroCdkn2dtm1MaroCdkn2ctm1BbdCdkn2dtm1Maro
• increased circulating follicle stimulating hormone level_Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0001750I129X1SvJC57BL6Cdkn2dtm1MaroCdkn2dtm1MaroCdkn2dtm1Maro
• decreased germ cell number_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>,Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0002209I129P2OlaHsd129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2dtm1MaroCdkn2dtm1MaroCdkn2ctm1BbdCdkn2dtm1Maro
• enlarged testis_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>
  http://metadb.riken.jp/0001148I129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2ctm1Bbd
• abnormal Leydig cell differentiation_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>
  http://metadb.riken.jp/0013602I129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2ctm1Bbd
• abnormal spermatogenesis_Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0001156I129X1SvJC57BL6Cdkn2dtm1MaroCdkn2dtm1MaroCdkn2dtm1Maro
• oligozoospermia_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>,Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0002687I129P2OlaHsd129S1SvC57BL6Cdkn2ctm1BbdCdkn2ctm1BbdCdkn2dtm1MaroCdkn2dtm1MaroCdkn2ctm1BbdCdkn2dtm1Maro
• abnormal apoptosis_Cdkn2d<tm1Maro>/Cdkn2d<tm1Maro>
  http://metadb.riken.jp/0001648I129X1SvJC57BL6Cdkn2dtm1MaroCdkn2dtm1MaroCdkn2dtm1Maro