O. Dardenne, et.al., Targeted inactivation of the 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase gene (CYP27B1) creates an animal model of pseudovitamin D-deficiency rickets., Endocrinology, 2001, 142

http://rdf.ncbi.nlm.nih.gov/pubmed/11416036

O. Dardenne, et.al., Targeted inactivation of the 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase gene (CYP27B1) creates an animal model of pseudovitamin D-deficiency rickets., Endocrinology, 2001, 142

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cyp27b1<tm1Star>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182334

class

http://purl.org/net/cito/citesAsAuthority

• Cyp27b1<tm1Star>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182334

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• enlarged parathyroid gland_Cyp27b1<tm1Star>/Cyp27b1<tm1Star>
  http://metadb.riken.jp/0003112I129S1Sv129X1SvJCyp27b1tm1StarCyp27b1tm1StarCyp27b1tm1Star
• increased circulating parathyroid hormone level_Cyp27b1<tm1Star>/Cyp27b1<tm1Star>
  http://metadb.riken.jp/0002904I129S1Sv129X1SvJCyp27b1tm1StarCyp27b1tm1StarCyp27b1tm1Star
• decreased body size_Cyp27b1<tm1Star>/Cyp27b1<tm1Star>
  http://metadb.riken.jp/0001265I129S1Sv129X1SvJCyp27b1tm1StarCyp27b1tm1StarCyp27b1tm1Star
• increased circulating alkaline phosphatase level_Cyp27b1<tm1Star>/Cyp27b1<tm1Star>
  http://metadb.riken.jp/0002968I129S1Sv129X1SvJCyp27b1tm1StarCyp27b1tm1StarCyp27b1tm1Star
• slow postnatal weight gain_Cyp27b1<tm1Star>/Cyp27b1<tm1Star>
  http://metadb.riken.jp/0008489I129S1Sv129X1SvJCyp27b1tm1StarCyp27b1tm1StarCyp27b1tm1Star
• decreased bone mineralization_Cyp27b1<tm1Star>/Cyp27b1<tm1Star>
  http://metadb.riken.jp/0020137I129S1Sv129X1SvJCyp27b1tm1StarCyp27b1tm1StarCyp27b1tm1Star
• rickets_Cyp27b1<tm1Star>/Cyp27b1<tm1Star>
  http://metadb.riken.jp/0003116I129S1Sv129X1SvJCyp27b1tm1StarCyp27b1tm1StarCyp27b1tm1Star
• decreased circulating phosphate level_Cyp27b1<tm1Star>/Cyp27b1<tm1Star>
  http://metadb.riken.jp/0000198I129S1Sv129X1SvJCyp27b1tm1StarCyp27b1tm1StarCyp27b1tm1Star
• abnormal long bone metaphysis morphology_Cyp27b1<tm1Star>/Cyp27b1<tm1Star>
  http://metadb.riken.jp/0000133I129S1Sv129X1SvJCyp27b1tm1StarCyp27b1tm1StarCyp27b1tm1Star
• decreased circulating calcium level_Cyp27b1<tm1Star>/Cyp27b1<tm1Star>
  http://metadb.riken.jp/0000195I129S1Sv129X1SvJCyp27b1tm1StarCyp27b1tm1StarCyp27b1tm1Star
• abnormal blood homeostasis_Cyp27b1<tm1Star>/Cyp27b1<tm1Star>
  http://metadb.riken.jp/0009642I129S1Sv129X1SvJCyp27b1tm1StarCyp27b1tm1StarCyp27b1tm1Star
• postnatal growth retardation_Cyp27b1<tm1Star>/Cyp27b1<tm1Star>
  http://metadb.riken.jp/0001732I129S1Sv129X1SvJCyp27b1tm1StarCyp27b1tm1StarCyp27b1tm1Star
• decreased bone mineral density_Cyp27b1<tm1Star>/Cyp27b1<tm1Star>
  http://metadb.riken.jp/0000063I129S1Sv129X1SvJCyp27b1tm1StarCyp27b1tm1StarCyp27b1tm1Star
• increased long bone epiphyseal plate size_Cyp27b1<tm1Star>/Cyp27b1<tm1Star>
  http://metadb.riken.jp/0006398I129S1Sv129X1SvJCyp27b1tm1StarCyp27b1tm1StarCyp27b1tm1Star
• disorganized long bone epiphyseal plate_Cyp27b1<tm1Star>/Cyp27b1<tm1Star>
  http://metadb.riken.jp/0006397I129S1Sv129X1SvJCyp27b1tm1StarCyp27b1tm1StarCyp27b1tm1Star
• osteomalacia_Cyp27b1<tm1Star>/Cyp27b1<tm1Star>
  http://metadb.riken.jp/0009445I129S1Sv129X1SvJCyp27b1tm1StarCyp27b1tm1StarCyp27b1tm1Star