H. Ju, et.al., Conditional and targeted overexpression of vascular chymase causes hypertension in transgenic mice., Proceedings of the National Academy of Sciences of the United States of America, 2001, 98

http://rdf.ncbi.nlm.nih.gov/pubmed/11416217

H. Ju, et.al., Conditional and targeted overexpression of vascular chymase causes hypertension in transgenic mice., Proceedings of the National Academy of Sciences of the United States of America, 2001, 98

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Tagln-tTA)1Mrab
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447082
• Tg(tetO-Mcpt1)1Mrab
  http://metadb.riken.jp/db/mgi_rdf/MGI:3772577

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Tagln-tTA)1Mrab
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447082
• Tg(tetO-Mcpt1)1Mrab
  http://metadb.riken.jp/db/mgi_rdf/MGI:3772577

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal aorta tunica media morphology_Tg(Tagln-tTA)1Mrab/0,Tg(tetO-Mcpt1)1Mrab/0
  http://metadb.riken.jp/0009873IC57BL6SJLTgTaglntTA1Mrab0TgtetOMcpt11Mrab0TgTaglntTA1MrabTgtetOMcpt11Mrab
• increased left ventricle weight_Tg(Tagln-tTA)1Mrab/0,Tg(tetO-Mcpt1)1Mrab/0
  http://metadb.riken.jp/0003915IC57BL6SJLTgTaglntTA1Mrab0TgtetOMcpt11Mrab0TgTaglntTA1MrabTgtetOMcpt11Mrab
• no abnormal phenotype detected_Tg(Tagln-tTA)1Mrab/0
  http://metadb.riken.jp/0002169IC57BL6SJLTgTaglntTA1Mrab0TgTaglntTA1Mrab
• abnormal artery morphology_Tg(Tagln-tTA)1Mrab/0,Tg(tetO-Mcpt1)1Mrab/0
  http://metadb.riken.jp/0002191IC57BL6SJLTgTaglntTA1Mrab0TgtetOMcpt11Mrab0TgTaglntTA1MrabTgtetOMcpt11Mrab
• increased systemic arterial systolic blood pressure_Tg(Tagln-tTA)1Mrab/0,Tg(tetO-Mcpt1)1Mrab/0
  http://metadb.riken.jp/0006144IC57BL6SJLTgTaglntTA1Mrab0TgtetOMcpt11Mrab0TgTaglntTA1MrabTgtetOMcpt11Mrab
• no abnormal phenotype detected_Tg(tetO-Mcpt1)1Mrab/0
  http://metadb.riken.jp/0002169IC57BL6SJLTgtetOMcpt11Mrab0TgtetOMcpt11Mrab
• increased cell proliferation_Tg(Tagln-tTA)1Mrab/0,Tg(tetO-Mcpt1)1Mrab/0
  http://metadb.riken.jp/0000351IC57BL6SJLTgTaglntTA1Mrab0TgtetOMcpt11Mrab0TgTaglntTA1MrabTgtetOMcpt11Mrab
• increased vasoconstriction_Tg(Tagln-tTA)1Mrab/0,Tg(tetO-Mcpt1)1Mrab/0
  http://metadb.riken.jp/0003025IC57BL6SJLTgTaglntTA1Mrab0TgtetOMcpt11Mrab0TgTaglntTA1MrabTgtetOMcpt11Mrab
• abnormal vasoconstriction_Tg(Tagln-tTA)1Mrab/0,Tg(tetO-Mcpt1)1Mrab/0
  http://metadb.riken.jp/0000250IC57BL6SJLTgTaglntTA1Mrab0TgtetOMcpt11Mrab0TgTaglntTA1MrabTgtetOMcpt11Mrab
• increased mean systemic arterial blood pressure_Tg(Tagln-tTA)1Mrab/0,Tg(tetO-Mcpt1)1Mrab/0
  http://metadb.riken.jp/0004875IC57BL6SJLTgTaglntTA1Mrab0TgtetOMcpt11Mrab0TgTaglntTA1MrabTgtetOMcpt11Mrab