D K. Panda, et.al., Targeted ablation of the 25-hydroxyvitamin D 1alpha -hydroxylase enzyme: evidence for skeletal, reproductive, and immune dysfunction., Proceedings of the National Academy of Sciences of the United States of America, 2001, 98

http://rdf.ncbi.nlm.nih.gov/pubmed/11416220

http://rdf.ncbi.nlm.nih.gov/pubmed/11416220

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182323

class

http://purl.org/net/cito/citesAsAuthority

• Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182323

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• small uterus_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0002637I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• enlarged lymph nodes_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0000702I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• endometrium hypoplasia_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0009091I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• absent corpus luteum_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0001134I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• decreased bone mineralization_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0020137I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• decreased T cell number_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0005018I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• abnormal ovarian folliculogenesis_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0001130I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• thickened long bone epiphysis_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0000132I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• decreased osteoclast cell number_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0004985I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• small ovary_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0001127I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• absent estrous cycle_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0009009I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• increased circulating parathyroid hormone level_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0002904I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• postnatal growth retardation_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0001732I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• decreased circulating calcium level_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0000195I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• decreased body weight_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0001262I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• female infertility_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0001926I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• decreased circulating phosphate level_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0000198I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• absent mature ovarian follicles_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0001132I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• increased urine phosphate level_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0002901I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• anovulation_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0008869I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• increased circulating alkaline phosphatase level_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0002968I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo
• abnormal blood homeostasis_Cyp27b1<tm1Dgo>/Cyp27b1<tm1Dgo>
  http://metadb.riken.jp/0009642I129S1Sv129X1SvJBALBcCyp27b1tm1DgoCyp27b1tm1DgoCyp27b1tm1Dgo