A H. Hasty, et.al., Severe hypercholesterolemia, hypertriglyceridemia, and atherosclerosis in mice lacking both leptin and the low density lipoprotein receptor., The Journal of biological chemistry, 2001, 276

http://rdf.ncbi.nlm.nih.gov/pubmed/11445560

A H. Hasty, et.al., Severe hypercholesterolemia, hypertriglyceridemia, and atherosclerosis in mice lacking both leptin and the low density lipoprotein receptor., The Journal of biological chemistry, 2001, 276

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased circulating HDL cholesterol level_Ldlr<tm1Her>/Ldlr<tm1Her>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001556B6CgLepobLdlrtm1HerLdlrtm1HerLdlrtm1HerLepobLepobLepobLdlrtm1Her
• increased circulating cholesterol level_Ldlr<tm1Her>/Ldlr<tm1Her>
  http://metadb.riken.jp/0005178B6129S7Ldlrtm1HerLdlrtm1HerLdlrtm1HerLdlrtm1Her
• increased circulating cholesterol level_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0005178IC57BL6LepobLepobLepob
• increased circulating triglyceride level_Ldlr<tm1Her>/Ldlr<tm1Her>
  http://metadb.riken.jp/0001552B6129S7Ldlrtm1HerLdlrtm1HerLdlrtm1HerLdlrtm1Her
• abnormal circulating cholesterol level_Ldlr<tm1Her>/Ldlr<tm1Her>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0000180B6CgLepobLdlrtm1HerLdlrtm1HerLdlrtm1HerLepobLepobLepobLdlrtm1Her
• increased circulating cholesterol level_Ldlr<tm1Her>/Ldlr<+>
  http://metadb.riken.jp/0005178B6129S7Ldlrtm1HerLdlrtm1HerLdlrLdlrLdlrtm1Her
• increased liver triglyceride level_Ldlr<tm1Her>/Ldlr<+>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0009355B6CgLepobLdlrtm1HerLdlrtm1HerLdlrLepobLepobLepobLdlrLdlrtm1Her
• increased circulating triglyceride level_Ldlr<tm1Her>/Ldlr<+>
  http://metadb.riken.jp/0001552B6129S7Ldlrtm1HerLdlrtm1HerLdlrLdlrLdlrtm1Her
• increased liver triglyceride level_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0009355IC57BL6LepobLepobLepob
• increased circulating cholesterol level_Ldlr<tm1Her>/Ldlr<tm1Her>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0005178B6CgLepobLdlrtm1HerLdlrtm1HerLdlrtm1HerLepobLepobLepobLdlrtm1Her
• hyperlipidemia_Ldlr<tm1Her>/Ldlr<tm1Her>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001548B6CgLepobLdlrtm1HerLdlrtm1HerLdlrtm1HerLepobLepobLepobLdlrtm1Her
• increased liver triglyceride level_Ldlr<tm1Her>/Ldlr<tm1Her>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0009355B6CgLepobLdlrtm1HerLdlrtm1HerLdlrtm1HerLepobLepobLepobLdlrtm1Her
• increased circulating HDL cholesterol level_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001556IC57BL6LepobLepobLepob
• increased circulating triglyceride level_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001552IC57BL6LepobLepobLepob
• increased circulating HDL cholesterol level_Ldlr<tm1Her>/Ldlr<tm1Her>
  http://metadb.riken.jp/0001556B6129S7Ldlrtm1HerLdlrtm1HerLdlrtm1HerLdlrtm1Her
• increased liver cholesterol level_Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0010027IC57BL6LepobLepobLepob
• increased circulating cholesterol level_Ldlr<tm1Her>/Ldlr<+>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0005178B6CgLepobLdlrtm1HerLdlrtm1HerLdlrLepobLepobLepobLdlrLdlrtm1Her
• increased liver cholesterol level_Ldlr<tm1Her>/Ldlr<tm1Her>
  http://metadb.riken.jp/0010027B6129S7Ldlrtm1HerLdlrtm1HerLdlrtm1HerLdlrtm1Her
• atherosclerotic lesions_Ldlr<tm1Her>/Ldlr<tm1Her>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0005338B6CgLepobLdlrtm1HerLdlrtm1HerLdlrtm1HerLepobLepobLepobLdlrtm1Her
• increased circulating LDL cholesterol level_Ldlr<tm1Her>/Ldlr<tm1Her>
  http://metadb.riken.jp/0000182B6129S7Ldlrtm1HerLdlrtm1HerLdlrtm1HerLdlrtm1Her
• increased circulating HDL cholesterol level_Ldlr<tm1Her>/Ldlr<+>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001556B6CgLepobLdlrtm1HerLdlrtm1HerLdlrLepobLepobLepobLdlrLdlrtm1Her
• increased liver cholesterol level_Ldlr<tm1Her>/Ldlr<+>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0010027B6CgLepobLdlrtm1HerLdlrtm1HerLdlrLepobLepobLepobLdlrLdlrtm1Her
• increased liver cholesterol level_Ldlr<tm1Her>/Ldlr<tm1Her>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0010027B6CgLepobLdlrtm1HerLdlrtm1HerLdlrtm1HerLepobLepobLepobLdlrtm1Her
• increased circulating triglyceride level_Ldlr<tm1Her>/Ldlr<tm1Her>,Lep<ob>/Lep<ob>
  http://metadb.riken.jp/0001552B6CgLepobLdlrtm1HerLdlrtm1HerLdlrtm1HerLepobLepobLepobLdlrtm1Her

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased circulating cholesterol level in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010951
• increased circulating HDL cholesterol level in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010706
• increased liver cholesterol level in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1006455
• increased liver triglyceride level in RBRC03708
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010724