J L. Michaud, et.al., Sim1 haploinsufficiency causes hyperphagia, obesity and reduction of the paraventricular nucleus of the hypothalamus., Human molecular genetics, 2001, 10

http://rdf.ncbi.nlm.nih.gov/pubmed/11448938

J L. Michaud, et.al., Sim1 haploinsufficiency causes hyperphagia, obesity and reduction of the paraventricular nucleus of the hypothalamus., Human molecular genetics, 2001, 10

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased circulating insulin level_Sim1<tm1Fan>/Sim1<+>
  http://metadb.riken.jp/0002079I129SvC57BL6Sim1tm1FanSim1Sim1tm1FanSim1
• increased white adipose tissue amount_Sim1<tm1Fan>/Sim1<+>
  http://metadb.riken.jp/0000008I129SvC57BL6Sim1tm1FanSim1Sim1tm1FanSim1
• abnormal white adipose tissue morphology_Sim1<tm1Fan>/Sim1<+>
  http://metadb.riken.jp/0002970I129SvC57BL6Sim1tm1FanSim1Sim1tm1FanSim1
• increased brown adipose tissue amount_Sim1<tm1Fan>/Sim1<+>
  http://metadb.riken.jp/0000005I129SvC57BL6Sim1tm1FanSim1Sim1tm1FanSim1
• abnormal glucose homeostasis_Sim1<tm1Fan>/Sim1<+>
  http://metadb.riken.jp/0002078I129SvC57BL6Sim1tm1FanSim1Sim1tm1FanSim1
• polyphagia_Sim1<tm1Fan>/Sim1<+>
  http://metadb.riken.jp/0001433I129SvC57BL6Sim1tm1FanSim1Sim1tm1FanSim1
• increased susceptibility to weight gain_Sim1<tm1Fan>/Sim1<+>
  http://metadb.riken.jp/0005455I129SvC57BL6Sim1tm1FanSim1Sim1tm1FanSim1
• abnormal brown adipose tissue morphology_Sim1<tm1Fan>/Sim1<+>
  http://metadb.riken.jp/0002971I129SvC57BL6Sim1tm1FanSim1Sim1tm1FanSim1
• increased body length_Sim1<tm1Fan>/Sim1<+>
  http://metadb.riken.jp/0001257I129SvC57BL6Sim1tm1FanSim1Sim1tm1FanSim1