L B. Meira, et.al., Heterozygosity for the mouse Apex gene results in phenotypes associated with oxidative stress., Cancer research, 2001, 61

http://rdf.ncbi.nlm.nih.gov/pubmed/11454706

L B. Meira, et.al., Heterozygosity for the mouse Apex gene results in phenotypes associated with oxidative stress., Cancer research, 2001, 61

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Apex1<tm1Ecf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2652193

class

http://purl.org/net/cito/citesAsAuthority

• Apex1<tm1Ecf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2652193

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased tumor incidence_Apex1<tm1Ecf>/Apex1<+>
  http://metadb.riken.jp/0002020EI129SvorI129SvC57BL6Apex1tm1EcfApex1Apex1Apex1tm1Ecf
• decreased cellular sensitivity to ultraviolet irradiation_Apex1<tm1Ecf>/Apex1<+>
  http://metadb.riken.jp/0008411EI129SvorI129SvC57BL6Apex1tm1EcfApex1Apex1Apex1tm1Ecf
• myocarditis_Apex1<tm1Ecf>/Apex1<+>
  http://metadb.riken.jp/0001856EI129SvorI129SvC57BL6Apex1tm1EcfApex1Apex1Apex1tm1Ecf
• abnormal cell death_Apex1<tm1Ecf>/Apex1<+>
  http://metadb.riken.jp/0000313EI129SvorI129SvC57BL6Apex1tm1EcfApex1Apex1Apex1tm1Ecf
• increased tumor incidence_Apex1<tm1Ecf>/Apex1<+>,Xpc<tm1Ecf>/Xpc<tm1Ecf>
  http://metadb.riken.jp/0002020I129Apex1tm1EcfApex1Xpctm1EcfXpctm1EcfXpctm1EcfApex1tm1EcfApex1
• heart inflammation_Apex1<tm1Ecf>/Apex1<+>
  http://metadb.riken.jp/0001853EI129SvorI129SvC57BL6Apex1tm1EcfApex1Apex1Apex1tm1Ecf
• increased carcinoma incidence_Apex1<tm1Ecf>/Apex1<+>
  http://metadb.riken.jp/0002038EI129SvorI129SvC57BL6Apex1tm1EcfApex1Apex1Apex1tm1Ecf
• pericarditis_Apex1<tm1Ecf>/Apex1<+>
  http://metadb.riken.jp/0001857EI129SvorI129SvC57BL6Apex1tm1EcfApex1Apex1Apex1tm1Ecf
• prenatal lethality, incomplete penetrance_Apex1<tm1Ecf>/Apex1<+>
  http://metadb.riken.jp/0011101EI129SvorI129SvC57BL6Apex1tm1EcfApex1Apex1Apex1tm1Ecf
• embryonic lethality between implantation and somite formation, complete penetrance_Apex1<tm1Ecf>/Apex1<tm1Ecf>
  http://metadb.riken.jp/0011096EI129SvorI129SvC57BL6Apex1tm1EcfApex1tm1EcfApex1tm1Ecf
• increased lymphoma incidence_Apex1<tm1Ecf>/Apex1<+>
  http://metadb.riken.jp/0012431EI129SvorI129SvC57BL6Apex1tm1EcfApex1Apex1Apex1tm1Ecf
• oxidative stress_Apex1<tm1Ecf>/Apex1<+>,Xpc<tm1Ecf>/Xpc<tm1Ecf>
  http://metadb.riken.jp/0003674I129Apex1tm1EcfApex1Xpctm1EcfXpctm1EcfXpctm1EcfApex1tm1EcfApex1
• increased sarcoma incidence_Apex1<tm1Ecf>/Apex1<+>
  http://metadb.riken.jp/0002032EI129SvorI129SvC57BL6Apex1tm1EcfApex1Apex1Apex1tm1Ecf
• cardiac fibrosis_Apex1<tm1Ecf>/Apex1<+>
  http://metadb.riken.jp/0003141EI129SvorI129SvC57BL6Apex1tm1EcfApex1Apex1Apex1tm1Ecf
• increased cellular sensitivity to oxidative stress_Apex1<tm1Ecf>/Apex1<+>
  http://metadb.riken.jp/0008412EI129SvorI129SvC57BL6Apex1tm1EcfApex1Apex1Apex1tm1Ecf
• oxidative stress_Xpc<tm1Ecf>/Xpc<tm1Ecf>
  http://metadb.riken.jp/0003674I129Xpctm1EcfXpctm1EcfXpctm1Ecf