J. Ko, et.al., p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, 21

http://rdf.ncbi.nlm.nih.gov/pubmed/11517264

J. Ko, et.al., p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, 21

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cdk5r2<tm1Lht>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2387662

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal neuron differentiation_Cdk5r1<tm1Lht>/Cdk5r1<+>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0009937I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1Cdk5r2tm1LhtCdk5r2tm1LhtCdk5r1Cdk5r1tm1LhtCdk5r2tm1Lht
• decreased embryo size_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0001698I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r1tm1Lht
• unresponsive to tactile stimuli_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0001491I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r1tm1Lht
• chromatolysis_Cdk5<tm1Kul>/Cdk5<tm1Kul>
  http://metadb.riken.jp/0002883I129S4SvJaeC57BL6Cdk5tm1KulCdk5tm1KulCdk5tm1Kul
• abnormal cortical plate morphology_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0008439I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r1tm1Lht
• abnormal cerebellum external granule cell layer morphology_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0000872I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r1tm1Lht
• small cerebellum_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<+>
  http://metadb.riken.jp/0000852I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2Cdk5r2tm1LhtCdk5r1tm1LhtCdk5r2
• abnormal cortical plate morphology_Cdk5<tm1Kul>/Cdk5<tm1Kul>
  http://metadb.riken.jp/0008439I129S4SvJaeC57BL6Cdk5tm1KulCdk5tm1KulCdk5tm1Kul
• perinatal lethality, incomplete penetrance_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0011090I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r1tm1Lht
• small cerebellum_Cdk5r1<tm1Lht>/Cdk5r1<+>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0000852I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1Cdk5r2tm1LhtCdk5r2tm1LhtCdk5r1Cdk5r1tm1LhtCdk5r2tm1Lht
• abnormal cerebral cortex morphology_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0000788I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r1tm1Lht
• abnormal motor neuron morphology_Cdk5<tm1Kul>/Cdk5<tm1Kul>
  http://metadb.riken.jp/0000937I129S4SvJaeC57BL6Cdk5tm1KulCdk5tm1KulCdk5tm1Kul
• premature death_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<+>
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2Cdk5r2tm1LhtCdk5r1tm1LhtCdk5r2
• abnormal hippocampus morphology_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>
  http://metadb.riken.jp/0000807I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r1tm1Lht
• abnormal neuron differentiation_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0009937I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r1tm1Lht
• abnormal cerebellum development_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0000854I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r1tm1Lht
• abnormal cerebellum morphology_Cdk5r1<tm1Lht>/Cdk5r1<+>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0000849I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1Cdk5r2tm1LhtCdk5r2tm1LhtCdk5r1Cdk5r1tm1LhtCdk5r2tm1Lht
• abnormal motor neuron morphology_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0000937I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r1tm1Lht
• abnormal cortical marginal zone morphology_Cdk5r1<tm1Lht>/Cdk5r1<+>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0000792I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1Cdk5r2tm1LhtCdk5r2tm1LhtCdk5r1Cdk5r1tm1LhtCdk5r2tm1Lht
• abnormal hippocampus layer morphology_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<+>
  http://metadb.riken.jp/0000813I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2Cdk5r2tm1LhtCdk5r1tm1LhtCdk5r2
• abnormal olfactory bulb development_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0002739I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r1tm1Lht
• abnormal dentate gyrus morphology_Cdk5<tm1Kul>/Cdk5<tm1Kul>
  http://metadb.riken.jp/0000812I129S4SvJaeC57BL6Cdk5tm1KulCdk5tm1KulCdk5tm1Kul
• small cerebellum_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0000852I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r1tm1Lht
• abnormal cortical marginal zone morphology_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0000792I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r1tm1Lht
• abnormal olfactory bulb development_Cdk5<tm1Kul>/Cdk5<tm1Kul>
  http://metadb.riken.jp/0002739I129S4SvJaeC57BL6Cdk5tm1KulCdk5tm1KulCdk5tm1Kul
• abnormal subplate morphology_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>
  http://metadb.riken.jp/0008440I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r1tm1Lht
• abnormal cerebellum morphology_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<+>
  http://metadb.riken.jp/0000849I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2Cdk5r2tm1LhtCdk5r1tm1LhtCdk5r2
• absent Purkinje cell layer_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0009718I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r1tm1Lht
• absent cerebellar foliation_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0000853I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r1tm1Lht
• no abnormal phenotype detected_Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0002169I129S4SvJaeC57BL6Cdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1Lht
• thin cortical plate_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0008441I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r1tm1Lht
• abnormal cerebral cortex morphology_Cdk5<tm1Kul>/Cdk5<tm1Kul>
  http://metadb.riken.jp/0000788I129S4SvJaeC57BL6Cdk5tm1KulCdk5tm1KulCdk5tm1Kul
• abnormal cerebral cortex morphology_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>
  http://metadb.riken.jp/0000788I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r1tm1Lht
• thin cortical plate_Cdk5r1<tm1Lht>/Cdk5r1<+>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0008441I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1Cdk5r2tm1LhtCdk5r2tm1LhtCdk5r1Cdk5r1tm1LhtCdk5r2tm1Lht
• abnormal hippocampus layer morphology_Cdk5<tm1Kul>/Cdk5<tm1Kul>
  http://metadb.riken.jp/0000813I129S4SvJaeC57BL6Cdk5tm1KulCdk5tm1KulCdk5tm1Kul
• weakness_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0000746I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r1tm1Lht
• abnormal hippocampus layer morphology_Cdk5r1<tm1Lht>/Cdk5r1<+>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0000813I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1Cdk5r2tm1LhtCdk5r2tm1LhtCdk5r1Cdk5r1tm1LhtCdk5r2tm1Lht
• abnormal dentate gyrus morphology_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0000812I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r1tm1Lht
• abnormal hippocampus layer morphology_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0000813I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r1tm1Lht
• chromatolysis_Cdk5r1<tm1Lht>/Cdk5r1<tm1Lht>,Cdk5r2<tm1Lht>/Cdk5r2<tm1Lht>
  http://metadb.riken.jp/0002883I129S4SvJaeC57BL6Cdk5r1tm1LhtCdk5r1tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r2tm1LhtCdk5r1tm1Lht

class

http://purl.org/net/cito/citesAsAuthority

• Cdk5r2<tm1Lht>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2387662

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD03153
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03153
• CD05777
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD05777