T. Kume, et.al., The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis., Genes & development, 2001, 15

http://rdf.ncbi.nlm.nih.gov/pubmed/11562355

http://rdf.ncbi.nlm.nih.gov/pubmed/11562355

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• dilated dorsal aorta_Foxc1<tm1Blh>/Foxc1<tm1Blh>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0004068I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1tm1BlhFoxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc2tm1Blh
• embryonic lethality during organogenesis, complete penetrance_Foxc1<tm1Blh>/Foxc1<tm1Blh>,Foxc2<tm1Blh>/Foxc2<+>
  http://metadb.riken.jp/0011098I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1tm1BlhFoxc2tm1BlhFoxc2Foxc2tm1BlhFoxc1tm1BlhFoxc2
• enlarged pericardium_Foxc1<tm1Blh>/Foxc1<tm1Blh>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0000291I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1tm1BlhFoxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc2tm1Blh
• abnormal third pharyngeal arch artery morphology_Foxc1<tm1Blh>/Foxc1<+>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0006356I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1Foxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc1Foxc2tm1Blh
• small heart_Foxc1<tm1Blh>/Foxc1<tm1Blh>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0002188I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1tm1BlhFoxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc2tm1Blh
• absent second pharyngeal arch_Foxc1<tm1Blh>/Foxc1<tm1Blh>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0006345I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1tm1BlhFoxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc2tm1Blh
• decreased somite size_Foxc1<tm1Blh>/Foxc1<+>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0011732I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1Foxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc1Foxc2tm1Blh
• incomplete rostral neuropore closure_Foxc1<tm1Blh>/Foxc1<tm1Blh>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0000928I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1tm1BlhFoxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc2tm1Blh
• abnormal vitelline vascular remodeling_Foxc1<tm1Blh>/Foxc1<tm1Blh>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0004076I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1tm1BlhFoxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc2tm1Blh
• abnormal somite shape_Foxc1<tm1Blh>/Foxc1<+>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0001691I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1Foxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc1Foxc2tm1Blh
• abnormal craniofacial development_Foxc1<tm1Blh>/Foxc1<tm1Blh>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0003935I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1tm1BlhFoxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc2tm1Blh
• abnormal pharyngeal arch artery morphology_Foxc1<tm1Blh>/Foxc1<+>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0002672I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1Foxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc1Foxc2tm1Blh
• embryonic lethality during organogenesis, complete penetrance_Foxc1<tm1Blh>/Foxc1<tm1Blh>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0011098I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1tm1BlhFoxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc2tm1Blh
• embryonic lethality during organogenesis, complete penetrance_Foxc1<tm1Blh>/Foxc1<+>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0011098I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1Foxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc1Foxc2tm1Blh
• abnormal dorsal-ventral polarity of the somites_Foxc1<tm1Blh>/Foxc1<tm1Blh>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0005223I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1tm1BlhFoxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc2tm1Blh
• abnormal vascular development_Foxc1<tm1Blh>/Foxc1<+>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0000259I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1Foxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc1Foxc2tm1Blh
• absent paraxial mesoderm_Foxc1<tm1Blh>/Foxc1<tm1Blh>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0012184I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1tm1BlhFoxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc2tm1Blh
• abnormal dorsal aorta morphology_Foxc1<tm1Blh>/Foxc1<tm1Blh>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0004787I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1tm1BlhFoxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc2tm1Blh
• absent second pharyngeal arch_Foxc1<tm1Blh>/Foxc1<+>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0006345I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1Foxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc1Foxc2tm1Blh
• small first pharyngeal arch_Foxc1<tm1Blh>/Foxc1<tm1Blh>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0006341I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1tm1BlhFoxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc2tm1Blh
• absent somites_Foxc1<tm1Blh>/Foxc1<tm1Blh>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0006386I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1tm1BlhFoxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc2tm1Blh
• decreased embryo size_Foxc1<tm1Blh>/Foxc1<tm1Blh>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0001698I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1tm1BlhFoxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc2tm1Blh
• disorganized myocardium_Foxc1<tm1Blh>/Foxc1<tm1Blh>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0002190I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1tm1BlhFoxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc2tm1Blh
• abnormal vascular development_Foxc1<tm1Blh>/Foxc1<tm1Blh>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0000259I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1tm1BlhFoxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc2tm1Blh
• abnormal pharyngeal pouch morphology_Foxc1<tm1Blh>/Foxc1<tm1Blh>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0006031I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1tm1BlhFoxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc2tm1Blh
• abnormal heartbeat_Foxc1<tm1Blh>/Foxc1<tm1Blh>,Foxc2<tm1Blh>/Foxc2<tm1Blh>
  http://metadb.riken.jp/0004085I129S6SvEvTacBlackSwissFoxc1tm1BlhFoxc1tm1BlhFoxc2tm1BlhFoxc2tm1BlhFoxc1tm1BlhFoxc2tm1Blh

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD19009
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD19009
• CD12427
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12427