B G. Bruneau, et.al., A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease., Cell, 2001, 106

http://rdf.ncbi.nlm.nih.gov/pubmed/11572777

B G. Bruneau, et.al., A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease., Cell, 2001, 106

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tbx5<tm1.1Jse>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2387851
• Tbx5<tm1Jse>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2387850

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• muscular ventricular septal defect_Tbx5<tm1.1Jse>/Tbx5<+>
  http://metadb.riken.jp/0010420I129SvBlackSwissTbx5tm11JseTbx5Tbx5tm11JseTbx5
• failure of heart looping_Tbx5<tm1.1Jse>/Tbx5<tm1.1Jse>
  http://metadb.riken.jp/0004251EI129SvEvorIBlackSwissTbx5tm11JseTbx5tm11JseTbx5tm11Jse
• abnormal impulse conducting system conduction_Tbx5<tm1.1Jse>/Tbx5<+>
  http://metadb.riken.jp/0003137I129SvBlackSwissTbx5tm11JseTbx5Tbx5tm11JseTbx5
• enlarged heart_Tbx5<tm1.1Jse>/Tbx5<+>
  http://metadb.riken.jp/0000274I129SvBlackSwissTbx5tm11JseTbx5Tbx5tm11JseTbx5
• abnormal carpal bone morphology_Tbx5<tm1.1Jse>/Tbx5<+>
  http://metadb.riken.jp/0000554I129SvBlackSwissTbx5tm11JseTbx5Tbx5tm11JseTbx5
• ventricular septal defect_Tbx5<tm1.1Jse>/Tbx5<+>
  http://metadb.riken.jp/0010402I129SvBlackSwissTbx5tm11JseTbx5Tbx5tm11JseTbx5
• absent atrioventricular cushions_Tbx5<tm1.1Jse>/Tbx5<tm1.1Jse>
  http://metadb.riken.jp/0000298EI129SvEvorIBlackSwissTbx5tm11JseTbx5tm11JseTbx5tm11Jse
• perinatal lethality, incomplete penetrance_Tbx5<tm1.1Jse>/Tbx5<+>
  http://metadb.riken.jp/0011090I129SvBlackSwissTbx5tm11JseTbx5Tbx5tm11JseTbx5
• abnormal heart ventricle morphology_Tbx5<tm1.1Jse>/Tbx5<+>
  http://metadb.riken.jp/0005294I129SvBlackSwissTbx5tm11JseTbx5Tbx5tm11JseTbx5
• common atrium_Tbx5<tm1.1Jse>/Tbx5<tm1.1Jse>
  http://metadb.riken.jp/0010406EI129SvEvorIBlackSwissTbx5tm11JseTbx5tm11JseTbx5tm11Jse
• embryonic growth arrest_Tbx5<tm1.1Jse>/Tbx5<tm1.1Jse>
  http://metadb.riken.jp/0001730EI129SvEvorIBlackSwissTbx5tm11JseTbx5tm11JseTbx5tm11Jse
• prolonged P wave_Tbx5<tm1.1Jse>/Tbx5<+>
  http://metadb.riken.jp/0004071I129SvBlackSwissTbx5tm11JseTbx5Tbx5tm11JseTbx5
• atrioventricular block_Tbx5<tm1.1Jse>/Tbx5<+>
  http://metadb.riken.jp/0010519I129SvBlackSwissTbx5tm11JseTbx5Tbx5tm11JseTbx5
• abnormal heart development_Tbx5<tm1.1Jse>/Tbx5<tm1.1Jse>
  http://metadb.riken.jp/0000267EI129SvEvorIBlackSwissTbx5tm11JseTbx5tm11JseTbx5tm11Jse
• abnormal heart tube morphology_Tbx5<tm1.1Jse>/Tbx5<tm1.1Jse>
  http://metadb.riken.jp/0000270EI129SvEvorIBlackSwissTbx5tm11JseTbx5tm11JseTbx5tm11Jse
• hydrops fetalis_Tbx5<tm1.1Jse>/Tbx5<+>
  http://metadb.riken.jp/0002192I129SvBlackSwissTbx5tm11JseTbx5Tbx5tm11JseTbx5
• perimembraneous ventricular septal defect_Tbx5<tm1.1Jse>/Tbx5<+>
  http://metadb.riken.jp/0010418I129SvBlackSwissTbx5tm11JseTbx5Tbx5tm11JseTbx5
• abnormal phalanx morphology_Tbx5<tm1.1Jse>/Tbx5<+>
  http://metadb.riken.jp/0005306I129SvBlackSwissTbx5tm11JseTbx5Tbx5tm11JseTbx5
• dilated heart atrium_Tbx5<tm1.1Jse>/Tbx5<+>
  http://metadb.riken.jp/0003140I129SvBlackSwissTbx5tm11JseTbx5Tbx5tm11JseTbx5
• pericardial effusion_Tbx5<tm1.1Jse>/Tbx5<+>
  http://metadb.riken.jp/0005312I129SvBlackSwissTbx5tm11JseTbx5Tbx5tm11JseTbx5
• embryonic lethality during organogenesis, complete penetrance_Tbx5<tm1.1Jse>/Tbx5<tm1.1Jse>
  http://metadb.riken.jp/0011098EI129SvEvorIBlackSwissTbx5tm11JseTbx5tm11JseTbx5tm11Jse
• sinoatrial block_Tbx5<tm1.1Jse>/Tbx5<+>
  http://metadb.riken.jp/0010520I129SvBlackSwissTbx5tm11JseTbx5Tbx5tm11JseTbx5
• prolonged PR interval_Tbx5<tm1.1Jse>/Tbx5<+>
  http://metadb.riken.jp/0003896I129SvBlackSwissTbx5tm11JseTbx5Tbx5tm11JseTbx5
• ostium primum atrial septal defect_Tbx5<tm1.1Jse>/Tbx5<+>
  http://metadb.riken.jp/0010404I129SvBlackSwissTbx5tm11JseTbx5Tbx5tm11JseTbx5

class

http://purl.org/net/cito/citesAsAuthority

• Tbx5<tm1.1Jse>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2387851
• Tbx5<tm1Jse>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2387850

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD21079
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD21079