R L. Tuttle, et.al., Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha., Nature medicine, 2001, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/11590437

R L. Tuttle, et.al., Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha., Nature medicine, 2001, 7

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Ins2-Akt1*)3Mbb
  http://metadb.riken.jp/db/mgi_rdf/MGI:5829193

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal pancreatic beta cell morphology_Tg(Ins2-Akt1*)3Mbb/0
  http://metadb.riken.jp/0005217IC57BL6SJLTgIns2Akt13Mbb0TgIns2Akt13Mbb
• improved glucose tolerance_Tg(Ins2-Akt1*)3Mbb/0
  http://metadb.riken.jp/0005292IC57BL6SJLTgIns2Akt13Mbb0TgIns2Akt13Mbb
• enlarged pancreatic islets_Tg(Ins2-Akt1*)3Mbb/0
  http://metadb.riken.jp/0009171IC57BL6SJLTgIns2Akt13Mbb0TgIns2Akt13Mbb
• abnormal pancreatic islet morphology_Tg(Ins2-Akt1*)3Mbb/0
  http://metadb.riken.jp/0005215IC57BL6SJLTgIns2Akt13Mbb0TgIns2Akt13Mbb
• increased circulating insulin level_Tg(Ins2-Akt1*)3Mbb/0
  http://metadb.riken.jp/0002079IC57BL6SJLTgIns2Akt13Mbb0TgIns2Akt13Mbb
• abnormal insulin secretion_Tg(Ins2-Akt1*)3Mbb/0
  http://metadb.riken.jp/0003564IC57BL6SJLTgIns2Akt13Mbb0TgIns2Akt13Mbb
• decreased circulating glucose level_Tg(Ins2-Akt1*)3Mbb/0
  http://metadb.riken.jp/0005560IC57BL6SJLTgIns2Akt13Mbb0TgIns2Akt13Mbb
• increased pancreatic islet number_Tg(Ins2-Akt1*)3Mbb/0
  http://metadb.riken.jp/0009167IC57BL6SJLTgIns2Akt13Mbb0TgIns2Akt13Mbb
• decreased susceptibility to non-insulin-dependent diabetes_Tg(Ins2-Akt1*)3Mbb/0
  http://metadb.riken.jp/0020088IC57BL6SJLTgIns2Akt13Mbb0TgIns2Akt13Mbb
• increased pancreatic beta cell mass_Tg(Ins2-Akt1*)3Mbb/0
  http://metadb.riken.jp/0009113IC57BL6SJLTgIns2Akt13Mbb0TgIns2Akt13Mbb
• abnormal pancreatic beta cell physiology_Tg(Ins2-Akt1*)3Mbb/0
  http://metadb.riken.jp/0003562IC57BL6SJLTgIns2Akt13Mbb0TgIns2Akt13Mbb
• decreased pancreatic beta cell number_Tg(Ins2-Akt1*)3Mbb/0
  http://metadb.riken.jp/0003339IC57BL6SJLTgIns2Akt13Mbb0TgIns2Akt13Mbb

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Ins2-Akt1*)3Mbb
  http://metadb.riken.jp/db/mgi_rdf/MGI:5829193