P. Liao, et.al., The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathy., Proceedings of the National Academy of Sciences of the United States of America, 2001, 98

http://rdf.ncbi.nlm.nih.gov/pubmed/11593045

P. Liao, et.al., The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathy., Proceedings of the National Academy of Sciences of the United States of America, 2001, 98

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Myh6-GFP,MAP2K3)58Ywa
  http://metadb.riken.jp/db/mgi_rdf/MGI:3581033
• Tg(Myh6-GFP,MAP2K6)8Ywa
  http://metadb.riken.jp/db/mgi_rdf/MGI:3581034

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal myocardial fiber morphology_Tg(Myh6-GFP,MAP2K3)58Ywa/?,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0000278I129S1Sv129X1SvJTgMyh6GFPMAP2K358YwaMyl2tm1creKrcMyl2Myl2Myl2tm1creKrcTgMyh6GFPMAP2K358Ywa
• respiratory distress_Tg(Myh6-GFP,MAP2K3)58Ywa/?,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0001954I129S1Sv129X1SvJTgMyh6GFPMAP2K358YwaMyl2tm1creKrcMyl2Myl2Myl2tm1creKrcTgMyh6GFPMAP2K358Ywa
• premature death_Tg(Myh6-GFP,MAP2K6)8Ywa/?,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJTgMyh6GFPMAP2K68YwaMyl2tm1creKrcMyl2TgMyh6GFPMAP2K68YwaMyl2tm1creKrcMyl2
• increased heart weight_Tg(Myh6-GFP,MAP2K6)8Ywa/?,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0002833I129S1Sv129X1SvJTgMyh6GFPMAP2K68YwaMyl2tm1creKrcMyl2TgMyh6GFPMAP2K68YwaMyl2tm1creKrcMyl2
• abnormal cardiovascular system physiology_Tg(Myh6-GFP,MAP2K6)8Ywa/?,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0001544I129S1Sv129X1SvJTgMyh6GFPMAP2K68YwaMyl2tm1creKrcMyl2TgMyh6GFPMAP2K68YwaMyl2tm1creKrcMyl2
• pulmonary edema_Tg(Myh6-GFP,MAP2K3)58Ywa/?,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0003828I129S1Sv129X1SvJTgMyh6GFPMAP2K358YwaMyl2tm1creKrcMyl2Myl2Myl2tm1creKrcTgMyh6GFPMAP2K358Ywa
• enlarged heart atrium_Tg(Myh6-GFP,MAP2K3)58Ywa/?,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0008725I129S1Sv129X1SvJTgMyh6GFPMAP2K358YwaMyl2tm1creKrcMyl2Myl2Myl2tm1creKrcTgMyh6GFPMAP2K358Ywa
• no abnormal phenotype detected_Tg(Myh6-GFP,MAP2K6)8Ywa/?
  http://metadb.riken.jp/0002169NSTgMyh6GFPMAP2K68YwaTgMyh6GFPMAP2K68Ywa
• respiratory distress_Tg(Myh6-GFP,MAP2K6)8Ywa/?,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0001954I129S1Sv129X1SvJTgMyh6GFPMAP2K68YwaMyl2tm1creKrcMyl2TgMyh6GFPMAP2K68YwaMyl2tm1creKrcMyl2
• cardiac interstitial fibrosis_Tg(Myh6-GFP,MAP2K3)58Ywa/?,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0005608I129S1Sv129X1SvJTgMyh6GFPMAP2K358YwaMyl2tm1creKrcMyl2Myl2Myl2tm1creKrcTgMyh6GFPMAP2K358Ywa
• pulmonary edema_Tg(Myh6-GFP,MAP2K6)8Ywa/?,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0003828I129S1Sv129X1SvJTgMyh6GFPMAP2K68YwaMyl2tm1creKrcMyl2TgMyh6GFPMAP2K68YwaMyl2tm1creKrcMyl2
• enlarged myocardial fiber_Tg(Myh6-GFP,MAP2K6)8Ywa/?,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0004564I129S1Sv129X1SvJTgMyh6GFPMAP2K68YwaMyl2tm1creKrcMyl2TgMyh6GFPMAP2K68YwaMyl2tm1creKrcMyl2
• premature death_Tg(Myh6-GFP,MAP2K3)58Ywa/?,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJTgMyh6GFPMAP2K358YwaMyl2tm1creKrcMyl2Myl2Myl2tm1creKrcTgMyh6GFPMAP2K358Ywa
• no abnormal phenotype detected_Tg(Myh6-GFP,MAP2K3)58Ywa/?
  http://metadb.riken.jp/0002169NSTgMyh6GFPMAP2K358YwaTgMyh6GFPMAP2K358Ywa
• abnormal cardiovascular system physiology_Tg(Myh6-GFP,MAP2K3)58Ywa/?,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0001544I129S1Sv129X1SvJTgMyh6GFPMAP2K358YwaMyl2tm1creKrcMyl2Myl2Myl2tm1creKrcTgMyh6GFPMAP2K358Ywa
• cardiac interstitial fibrosis_Tg(Myh6-GFP,MAP2K6)8Ywa/?,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0005608I129S1Sv129X1SvJTgMyh6GFPMAP2K68YwaMyl2tm1creKrcMyl2TgMyh6GFPMAP2K68YwaMyl2tm1creKrcMyl2
• increased heart weight_Tg(Myh6-GFP,MAP2K3)58Ywa/?,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0002833I129S1Sv129X1SvJTgMyh6GFPMAP2K358YwaMyl2tm1creKrcMyl2Myl2Myl2tm1creKrcTgMyh6GFPMAP2K358Ywa
• thin ventricular wall_Tg(Myh6-GFP,MAP2K3)58Ywa/?,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0000280I129S1Sv129X1SvJTgMyh6GFPMAP2K358YwaMyl2tm1creKrcMyl2Myl2Myl2tm1creKrcTgMyh6GFPMAP2K358Ywa
• enlarged heart atrium_Tg(Myh6-GFP,MAP2K6)8Ywa/?,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0008725I129S1Sv129X1SvJTgMyh6GFPMAP2K68YwaMyl2tm1creKrcMyl2TgMyh6GFPMAP2K68YwaMyl2tm1creKrcMyl2

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Myh6-GFP,MAP2K3)58Ywa
  http://metadb.riken.jp/db/mgi_rdf/MGI:3581033
• Tg(Myh6-GFP,MAP2K6)8Ywa
  http://metadb.riken.jp/db/mgi_rdf/MGI:3581034

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD22241
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD22241
• CD00975
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD00975