P. Cohen, et.al., Selective deletion of leptin receptor in neurons leads to obesity., The Journal of clinical investigation, 2001, 108

http://rdf.ncbi.nlm.nih.gov/pubmed/11602618

P. Cohen, et.al., Selective deletion of leptin receptor in neurons leads to obesity., The Journal of clinical investigation, 2001, 108

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Alb1-cre)1Rck
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176780
• Lepr<tm1.1Rck>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176775
• Lepr<tm1Rck>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176774

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Alb1-cre)1Rck
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176780
• Lepr<tm1.1Rck>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176775
• Lepr<tm1Rck>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176774

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• no abnormal phenotype detected_Lepr<tm1Rck>/Lepr<tm1.1Rck>,Tg(Alb1-cre)1Rck/0
  http://metadb.riken.jp/0002169I129P2OlaHsdC57BL6CBALeprtm1RckLeprtm11RckTgAlb1cre1Rck0Leprtm11RckLeprtm1RckTgAlb1cre1Rck
• increased circulating insulin level_Lepr<tm1Rck>/Lepr<tm1.1Rck>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0002079I129P2OlaHsdC57BL6CBALeprtm1RckLeprtm11RckTgSyn1cre671Jxm0Leprtm1RckLeprtm11RckTgSyn1cre671Jxm
• increased total body fat amount_Lepr<tm1Rck>/Lepr<tm1.1Rck>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0010024I129P2OlaHsdC57BL6CBALeprtm1RckLeprtm11RckTgSyn1cre671Jxm0Leprtm1RckLeprtm11RckTgSyn1cre671Jxm
• hepatic steatosis_Lepr<tm1Rck>/Lepr<tm1.1Rck>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0002628I129P2OlaHsdC57BL6CBALeprtm1RckLeprtm11RckTgSyn1cre671Jxm0Leprtm1RckLeprtm11RckTgSyn1cre671Jxm
• abnormal body composition_Lepr<tm1Rck>/Lepr<tm1.1Rck>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0005451I129P2OlaHsdC57BL6CBALeprtm1RckLeprtm11RckTgSyn1cre671Jxm0Leprtm1RckLeprtm11RckTgSyn1cre671Jxm
• no abnormal phenotype detected_Lepr<tm1Rck>/Lepr<tm1Rck>
  http://metadb.riken.jp/0002169I129SvLeprtm1RckLeprtm1RckLeprtm1Rck
• hyperglycemia_Lepr<tm1Rck>/Lepr<tm1.1Rck>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0001559I129P2OlaHsdC57BL6CBALeprtm1RckLeprtm11RckTgSyn1cre671Jxm0Leprtm1RckLeprtm11RckTgSyn1cre671Jxm
• obese_Lepr<tm1.1Rck>/Lepr<tm1.1Rck>
  http://metadb.riken.jp/0001261I129P2OlaHsdLeprtm11RckLeprtm11RckLeprtm11Rck
• increased circulating leptin level_Lepr<tm1Rck>/Lepr<tm1.1Rck>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0005669I129P2OlaHsdC57BL6CBALeprtm1RckLeprtm11RckTgSyn1cre671Jxm0Leprtm1RckLeprtm11RckTgSyn1cre671Jxm
• increased body weight_Lepr<tm1Rck>/Lepr<tm1.1Rck>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0001260I129P2OlaHsdC57BL6CBALeprtm1RckLeprtm11RckTgSyn1cre671Jxm0Leprtm1RckLeprtm11RckTgSyn1cre671Jxm