H. Seznec, et.al., Mice transgenic for the human myotonic dystrophy region with expanded CTG repeats display muscular and brain abnormalities., Human molecular genetics, 2001, 10

http://rdf.ncbi.nlm.nih.gov/pubmed/11726559

H. Seznec, et.al., Mice transgenic for the human myotonic dystrophy region with expanded CTG repeats display muscular and brain abnormalities., Human molecular genetics, 2001, 10

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal skeletal muscle fiber morphology_Tg(DMWD,DMPK*,SIX5)1177Ggo/0
  http://metadb.riken.jp/0003084IC57BL6DBA2TgDMWDDMPKSIX51177Ggo0TgDMWDDMPKSIX51177Ggo
• skeletal muscle fibrosis_Tg(DMWD,DMPK*,SIX5)328Ggo/0
  http://metadb.riken.jp/0009419IC57BL6DBA2TgDMWDDMPKSIX5328Ggo0TgDMWDDMPKSIX5328Ggo
• centrally nucleated skeletal muscle fibers_Tg(DMWD,DMPK*,SIX5)328Ggo/0
  http://metadb.riken.jp/0009404IC57BL6DBA2TgDMWDDMPKSIX5328Ggo0TgDMWDDMPKSIX5328Ggo
• abnormal tooth morphology_Tg(DMWD,DMPK*,SIX5)328Ggo/0
  http://metadb.riken.jp/0002100IC57BL6DBA2TgDMWDDMPKSIX5328Ggo0TgDMWDDMPKSIX5328Ggo
• decreased body size_Tg(DMWD,DMPK*,SIX5)328Ggo/0
  http://metadb.riken.jp/0001265IC57BL6DBA2TgDMWDDMPKSIX5328Ggo0TgDMWDDMPKSIX5328Ggo
• increased variability of skeletal muscle fiber size_Tg(DMWD,DMPK*,SIX5)328Ggo/0
  http://metadb.riken.jp/0009403IC57BL6DBA2TgDMWDDMPKSIX5328Ggo0TgDMWDDMPKSIX5328Ggo
• centrally nucleated skeletal muscle fibers_Tg(DMWD,DMPK*,SIX5)1177Ggo/0
  http://metadb.riken.jp/0009404IC57BL6DBA2TgDMWDDMPKSIX51177Ggo0TgDMWDDMPKSIX51177Ggo
• decreased body weight_Tg(DMWD,DMPK*,SIX5)328Ggo/0
  http://metadb.riken.jp/0001262IC57BL6DBA2TgDMWDDMPKSIX5328Ggo0TgDMWDDMPKSIX5328Ggo
• decreased body size_Tg(DMWD,DMPK*,SIX5)1177Ggo/Tg(DMWD,DMPK*,SIX5)1177Ggo
  http://metadb.riken.jp/0001265IC57BL6DBA2TgDMWDDMPKSIX51177GgoTgDMWDDMPKSIX51177GgoTgDMWDDMPKSIX51177Ggo
• abnormal skeletal muscle fiber morphology_Tg(DMWD,DMPK*,SIX5)328Ggo/0
  http://metadb.riken.jp/0003084IC57BL6DBA2TgDMWDDMPKSIX5328Ggo0TgDMWDDMPKSIX5328Ggo
• decreased litter size_Tg(DMWD,DMPK*,SIX5)1177Ggo/0
  http://metadb.riken.jp/0001935IC57BL6DBA2TgDMWDDMPKSIX51177Ggo0TgDMWDDMPKSIX51177Ggo
• abnormal brain morphology_Tg(DMWD,DMPK*,SIX5)1177Ggo/Tg(DMWD,DMPK*,SIX5)1177Ggo
  http://metadb.riken.jp/0002152IC57BL6DBA2TgDMWDDMPKSIX51177GgoTgDMWDDMPKSIX51177GgoTgDMWDDMPKSIX51177Ggo
• increased mitochondria size_Tg(DMWD,DMPK*,SIX5)1177Ggo/0
  http://metadb.riken.jp/0011630IC57BL6DBA2TgDMWDDMPKSIX51177Ggo0TgDMWDDMPKSIX51177Ggo
• muscular atrophy_Tg(DMWD,DMPK*,SIX5)1177Ggo/0
  http://metadb.riken.jp/0002269IC57BL6DBA2TgDMWDDMPKSIX51177Ggo0TgDMWDDMPKSIX51177Ggo
• premature death_Tg(DMWD,DMPK*,SIX5)328Ggo/Tg(DMWD,DMPK*,SIX5)328Ggo
  http://metadb.riken.jp/0002083IC57BL6DBA2TgDMWDDMPKSIX5328GgoTgDMWDDMPKSIX5328GgoTgDMWDDMPKSIX5328Ggo
• abnormal brain morphology_Tg(DMWD,DMPK*,SIX5)328Ggo/Tg(DMWD,DMPK*,SIX5)328Ggo
  http://metadb.riken.jp/0002152IC57BL6DBA2TgDMWDDMPKSIX5328GgoTgDMWDDMPKSIX5328GgoTgDMWDDMPKSIX5328Ggo
• increased variability of skeletal muscle fiber size_Tg(DMWD,DMPK*,SIX5)1177Ggo/Tg(DMWD,DMPK*,SIX5)1177Ggo
  http://metadb.riken.jp/0009403IC57BL6DBA2TgDMWDDMPKSIX51177GgoTgDMWDDMPKSIX51177GgoTgDMWDDMPKSIX51177Ggo
• abnormal tooth morphology_Tg(DMWD,DMPK*,SIX5)1177Ggo/0
  http://metadb.riken.jp/0002100IC57BL6DBA2TgDMWDDMPKSIX51177Ggo0TgDMWDDMPKSIX51177Ggo
• increased mitochondria number_Tg(DMWD,DMPK*,SIX5)1177Ggo/0
  http://metadb.riken.jp/0011628IC57BL6DBA2TgDMWDDMPKSIX51177Ggo0TgDMWDDMPKSIX51177Ggo
• abnormal tooth morphology_Tg(DMWD,DMPK*,SIX5)328Ggo/Tg(DMWD,DMPK*,SIX5)328Ggo
  http://metadb.riken.jp/0002100IC57BL6DBA2TgDMWDDMPKSIX5328GgoTgDMWDDMPKSIX5328GgoTgDMWDDMPKSIX5328Ggo
• impaired muscle relaxation_Tg(DMWD,DMPK*,SIX5)328Ggo/0
  http://metadb.riken.jp/0003157IC57BL6DBA2TgDMWDDMPKSIX5328Ggo0TgDMWDDMPKSIX5328Ggo
• increased variability of skeletal muscle fiber size_Tg(DMWD,DMPK*,SIX5)1177Ggo/0
  http://metadb.riken.jp/0009403IC57BL6DBA2TgDMWDDMPKSIX51177Ggo0TgDMWDDMPKSIX51177Ggo
• lethality, incomplete penetrance_Tg(DMWD,DMPK*,SIX5)328Ggo/Tg(DMWD,DMPK*,SIX5)328Ggo
  http://metadb.riken.jp/0010831IC57BL6DBA2TgDMWDDMPKSIX5328GgoTgDMWDDMPKSIX5328GgoTgDMWDDMPKSIX5328Ggo
• decreased body size_Tg(DMWD,DMPK*,SIX5)328Ggo/Tg(DMWD,DMPK*,SIX5)328Ggo
  http://metadb.riken.jp/0001265IC57BL6DBA2TgDMWDDMPKSIX5328GgoTgDMWDDMPKSIX5328GgoTgDMWDDMPKSIX5328Ggo
• skeletal muscle fibrosis_Tg(DMWD,DMPK*,SIX5)1177Ggo/0
  http://metadb.riken.jp/0009419IC57BL6DBA2TgDMWDDMPKSIX51177Ggo0TgDMWDDMPKSIX51177Ggo
• impaired muscle relaxation_Tg(DMWD,DMPK*,SIX5)328Ggo/Tg(DMWD,DMPK*,SIX5)328Ggo
  http://metadb.riken.jp/0003157IC57BL6DBA2TgDMWDDMPKSIX5328GgoTgDMWDDMPKSIX5328GgoTgDMWDDMPKSIX5328Ggo
• rectal prolapse_Tg(DMWD,DMPK*,SIX5)328Ggo/Tg(DMWD,DMPK*,SIX5)328Ggo
  http://metadb.riken.jp/0000493IC57BL6DBA2TgDMWDDMPKSIX5328GgoTgDMWDDMPKSIX5328GgoTgDMWDDMPKSIX5328Ggo
• decreased body size_Tg(DMWD,DMPK*,SIX5)1177Ggo/0
  http://metadb.riken.jp/0001265IC57BL6DBA2TgDMWDDMPKSIX51177Ggo0TgDMWDDMPKSIX51177Ggo
• impaired muscle relaxation_Tg(DMWD,DMPK*,SIX5)1177Ggo/Tg(DMWD,DMPK*,SIX5)1177Ggo
  http://metadb.riken.jp/0003157IC57BL6DBA2TgDMWDDMPKSIX51177GgoTgDMWDDMPKSIX51177GgoTgDMWDDMPKSIX51177Ggo
• increased variability of skeletal muscle fiber size_Tg(DMWD,DMPK*,SIX5)328Ggo/Tg(DMWD,DMPK*,SIX5)328Ggo
  http://metadb.riken.jp/0009403IC57BL6DBA2TgDMWDDMPKSIX5328GgoTgDMWDDMPKSIX5328GgoTgDMWDDMPKSIX5328Ggo
• skeletal muscle degeneration_Tg(DMWD,DMPK*,SIX5)1177Ggo/0
  http://metadb.riken.jp/0009415IC57BL6DBA2TgDMWDDMPKSIX51177Ggo0TgDMWDDMPKSIX51177Ggo