F. Long, et.al., Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation., Development (Cambridge, England), 2001, 128

http://rdf.ncbi.nlm.nih.gov/pubmed/11748145

F. Long, et.al., Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation., Development (Cambridge, England), 2001, 128

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(UAS-Smo*W539L)1Amc
  http://metadb.riken.jp/db/mgi_rdf/MGI:3584023
• Smo<tm2Amc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176256
• Tg(UAS-IHH)1Amc
  http://metadb.riken.jp/db/mgi_rdf/MGI:3584022
• Tg(Col2a1-cre)3Amc
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176263
• Tg(Col2a1-GAL4)1Amc
  http://metadb.riken.jp/db/mgi_rdf/MGI:3584024
• Tg(Col2a1-cre)15Amc
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176262
• Tg(Col2a1-cre)10Amc
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176264

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• short humerus_Smo<tm1Amc>/Smo<tm2Amc>,Tg(Col2a1-cre)10Amc/0
  http://metadb.riken.jp/0004351I129X1SvJSmotm1AmcSmotm2AmcTgCol2a1cre10Amc0TgCol2a1cre10AmcSmotm2AmcSmotm1Amc
• short fibula_Smo<tm1Amc>/Smo<tm2Amc>,Tg(Col2a1-cre)10Amc/0
  http://metadb.riken.jp/0002765I129X1SvJSmotm1AmcSmotm2AmcTgCol2a1cre10Amc0TgCol2a1cre10AmcSmotm2AmcSmotm1Amc
• short ulna_Smo<tm1Amc>/Smo<tm2Amc>,Tg(Col2a1-cre)10Amc/0
  http://metadb.riken.jp/0004359I129X1SvJSmotm1AmcSmotm2AmcTgCol2a1cre10Amc0TgCol2a1cre10AmcSmotm2AmcSmotm1Amc
• abnormal long bone epiphyseal plate proliferative zone_Tg(Col2a1-GAL4)1Amc/0,Tg(UAS-Smo*W539L)1Amc/0
  http://metadb.riken.jp/0003662NSTgCol2a1GAL41Amc0TgUASSmoW539L1Amc0TgUASSmoW539L1AmcTgCol2a1GAL41Amc
• abnormal skeleton development_Smo<tm1Amc>/Smo<tm2Amc>,Tg(Col2a1-cre)10Amc/0
  http://metadb.riken.jp/0002113I129X1SvJSmotm1AmcSmotm2AmcTgCol2a1cre10Amc0TgCol2a1cre10AmcSmotm2AmcSmotm1Amc
• short scapula_Smo<tm1Amc>/Smo<tm2Amc>,Tg(Col2a1-cre)10Amc/0
  http://metadb.riken.jp/0004340I129X1SvJSmotm1AmcSmotm2AmcTgCol2a1cre10Amc0TgCol2a1cre10AmcSmotm2AmcSmotm1Amc
• short humerus_Ihh<tm1Amc>/Ihh<tm1Amc>
  http://metadb.riken.jp/0004351I129S1Sv129X1SvJIhhtm1AmcIhhtm1AmcIhhtm1Amc
• abnormal chondrocyte morphology_Ihh<tm1Amc>/Ihh<tm1Amc>
  http://metadb.riken.jp/0000166I129S1Sv129X1SvJIhhtm1AmcIhhtm1AmcIhhtm1Amc
• short tibia_Smo<tm1Amc>/Smo<tm2Amc>,Tg(Col2a1-cre)10Amc/0
  http://metadb.riken.jp/0002764I129X1SvJSmotm1AmcSmotm2AmcTgCol2a1cre10Amc0TgCol2a1cre10AmcSmotm2AmcSmotm1Amc
• postnatal lethality, complete penetrance_Smo<tm1Amc>/Smo<tm2Amc>,Tg(Col2a1-cre)10Amc/0
  http://metadb.riken.jp/0011085I129X1SvJSmotm1AmcSmotm2AmcTgCol2a1cre10Amc0TgCol2a1cre10AmcSmotm2AmcSmotm1Amc
• abnormal skeleton development_Ihh<tm1Amc>/Ihh<tm1Amc>
  http://metadb.riken.jp/0002113I129S1Sv129X1SvJIhhtm1AmcIhhtm1AmcIhhtm1Amc
• short limbs_Smo<tm1Amc>/Smo<tm2Amc>,Tg(Col2a1-cre)10Amc/0
  http://metadb.riken.jp/0000547I129X1SvJSmotm1AmcSmotm2AmcTgCol2a1cre10Amc0TgCol2a1cre10AmcSmotm2AmcSmotm1Amc
• short limbs_Ihh<tm1Amc>/Ihh<tm1Amc>
  http://metadb.riken.jp/0000547I129S1Sv129X1SvJIhhtm1AmcIhhtm1AmcIhhtm1Amc
• short fibula_Ihh<tm1Amc>/Ihh<tm1Amc>
  http://metadb.riken.jp/0002765I129S1Sv129X1SvJIhhtm1AmcIhhtm1AmcIhhtm1Amc
• abnormal digit morphology_Smo<tm1Amc>/Smo<tm2Amc>,Tg(Col2a1-cre)10Amc/0
  http://metadb.riken.jp/0002110I129X1SvJSmotm1AmcSmotm2AmcTgCol2a1cre10Amc0TgCol2a1cre10AmcSmotm2AmcSmotm1Amc
• decreased length of long bones_Smo<tm1Amc>/Smo<tm2Amc>,Tg(Col2a1-cre)3Amc/0
  http://metadb.riken.jp/0004686I129X1SvJSmotm1AmcSmotm2AmcTgCol2a1cre3Amc0Smotm1AmcSmotm2AmcTgCol2a1cre3Amc
• abnormal long bone morphology_Ihh<tm1Amc>/Ihh<tm1Amc>
  http://metadb.riken.jp/0003723I129S1Sv129X1SvJIhhtm1AmcIhhtm1AmcIhhtm1Amc
• short scapula_Ihh<tm1Amc>/Ihh<tm1Amc>
  http://metadb.riken.jp/0004340I129S1Sv129X1SvJIhhtm1AmcIhhtm1AmcIhhtm1Amc
• decreased length of long bones_Smo<tm1Amc>/Smo<tm2Amc>,Tg(Col2a1-cre)10Amc/0
  http://metadb.riken.jp/0004686I129X1SvJSmotm1AmcSmotm2AmcTgCol2a1cre10Amc0TgCol2a1cre10AmcSmotm2AmcSmotm1Amc
• abnormal long bone epiphyseal plate proliferative zone_Tg(Col2a1-GAL4)1Amc/0,Tg(UAS-IHH)1Amc/0
  http://metadb.riken.jp/0003662NSTgCol2a1GAL41Amc0TgUASIHH1Amc0TgUASIHH1AmcTgCol2a1GAL41Amc
• decreased length of long bones_Smo<tm1Amc>/Smo<tm2Amc>,Tg(Col2a1-cre)15Amc/0
  http://metadb.riken.jp/0004686I129X1SvJSmotm1AmcSmotm2AmcTgCol2a1cre15Amc0Smotm2AmcSmotm1AmcTgCol2a1cre15Amc
• short tibia_Ihh<tm1Amc>/Ihh<tm1Amc>
  http://metadb.riken.jp/0002764I129S1Sv129X1SvJIhhtm1AmcIhhtm1AmcIhhtm1Amc
• abnormal chondrocyte morphology_Smo<tm1Amc>/Smo<tm2Amc>,Tg(Col2a1-cre)10Amc/0
  http://metadb.riken.jp/0000166I129X1SvJSmotm1AmcSmotm2AmcTgCol2a1cre10Amc0TgCol2a1cre10AmcSmotm2AmcSmotm1Amc
• short ulna_Ihh<tm1Amc>/Ihh<tm1Amc>
  http://metadb.riken.jp/0004359I129S1Sv129X1SvJIhhtm1AmcIhhtm1AmcIhhtm1Amc
• abnormal digit morphology_Ihh<tm1Amc>/Ihh<tm1Amc>
  http://metadb.riken.jp/0002110I129S1Sv129X1SvJIhhtm1AmcIhhtm1AmcIhhtm1Amc

class

http://purl.org/net/cito/citesAsAuthority

• Tg(UAS-Smo*W539L)1Amc
  http://metadb.riken.jp/db/mgi_rdf/MGI:3584023
• Smo<tm2Amc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176256
• Tg(UAS-IHH)1Amc
  http://metadb.riken.jp/db/mgi_rdf/MGI:3584022
• Tg(Col2a1-cre)3Amc
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176263
• Tg(Col2a1-GAL4)1Amc
  http://metadb.riken.jp/db/mgi_rdf/MGI:3584024
• Tg(Col2a1-cre)15Amc
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176262
• Tg(Col2a1-cre)10Amc
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176264