M. Murga, et.al., Mutation of E2F2 in mice causes enhanced T lymphocyte proliferation, leading to the development of autoimmunity., Immunity, 2001, 15

http://rdf.ncbi.nlm.nih.gov/pubmed/11754817

M. Murga, et.al., Mutation of E2F2 in mice causes enhanced T lymphocyte proliferation, leading to the development of autoimmunity., Immunity, 2001, 15

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal immune system morphology_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0000685I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• increased renal glomerulus basement membrane thickness_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0011409I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• abnormal immune system physiology_E2f2<tm1Zubi>/E2f2<tm1Zubi>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?
  http://metadb.riken.jp/0001790I129S1SvC57BL6C57BL6JDBA2JE2f2tm1ZubiE2f2tm1ZubiTgTcraHYTcrbHY71VboTgTcraHYTcrbHY71VboE2f2tm1Zubi
• abnormal skin morphology_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0002060I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• increased T cell proliferation_E2f2<tm1Zubi>/E2f2<tm1Zubi>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?
  http://metadb.riken.jp/0005348I129S1SvC57BL6C57BL6JDBA2JE2f2tm1ZubiE2f2tm1ZubiTgTcraHYTcrbHY71VboTgTcraHYTcrbHY71VboE2f2tm1Zubi
• increased anti-double stranded DNA antibody level_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0004762I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• liver inflammation_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0001860I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• reddish skin_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0001190I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• glomerulonephritis_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0002743I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• abnormal T cell differentiation_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0002145I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• enlarged spleen_E2f2<tm1Zubi>/E2f2<tm1Zubi>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?
  http://metadb.riken.jp/0000691I129S1SvC57BL6C57BL6JDBA2JE2f2tm1ZubiE2f2tm1ZubiTgTcraHYTcrbHY71VboTgTcraHYTcrbHY71VboE2f2tm1Zubi
• abnormal T cell subpopulation ratio_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0003944I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• progressive hair loss_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0009004I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• increased CD8-positive, alpha-beta T cell number_E2f2<tm1Zubi>/E2f2<tm1Zubi>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?
  http://metadb.riken.jp/0008078I129S1SvC57BL6C57BL6JDBA2JE2f2tm1ZubiE2f2tm1ZubiTgTcraHYTcrbHY71VboTgTcraHYTcrbHY71VboE2f2tm1Zubi
• increased susceptibility to autoimmune disorder_E2f2<tm1Zubi>/E2f2<tm1Zubi>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?
  http://metadb.riken.jp/0005350I129S1SvC57BL6C57BL6JDBA2JE2f2tm1ZubiE2f2tm1ZubiTgTcraHYTcrbHY71VboTgTcraHYTcrbHY71VboE2f2tm1Zubi
• increased memory T cell number_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0008049I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• increased inflammatory response_E2f2<tm1Zubi>/E2f2<tm1Zubi>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?
  http://metadb.riken.jp/0001846I129S1SvC57BL6C57BL6JDBA2JE2f2tm1ZubiE2f2tm1ZubiTgTcraHYTcrbHY71VboTgTcraHYTcrbHY71VboE2f2tm1Zubi
• increased spleen weight_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0004952I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• abnormal immune system morphology_E2f2<tm1Zubi>/E2f2<tm1Zubi>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?
  http://metadb.riken.jp/0000685I129S1SvC57BL6C57BL6JDBA2JE2f2tm1ZubiE2f2tm1ZubiTgTcraHYTcrbHY71VboTgTcraHYTcrbHY71VboE2f2tm1Zubi
• increased inflammatory response_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0001846I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• lung inflammation_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0001861I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• enlarged spleen_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0000691I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• thymus hypoplasia_E2f2<tm1Zubi>/E2f2<tm1Zubi>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?
  http://metadb.riken.jp/0001823I129S1SvC57BL6C57BL6JDBA2JE2f2tm1ZubiE2f2tm1ZubiTgTcraHYTcrbHY71VboTgTcraHYTcrbHY71VboE2f2tm1Zubi
• increased T cell proliferation_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0005348I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• decreased T cell proliferation_E2f1<tm1Meg>/E2f1<tm1Meg>
  http://metadb.riken.jp/0005095I129S4SvJaeC57BL6E2f1tm1MegE2f1tm1MegE2f1tm1Meg
• abnormal spleen white pulp morphology_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0002357I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• premature death_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0002083I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• abnormal immune system physiology_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0001790I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• premature death_E2f2<tm1Zubi>/E2f2<tm1Zubi>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?
  http://metadb.riken.jp/0002083I129S1SvC57BL6C57BL6JDBA2JE2f2tm1ZubiE2f2tm1ZubiTgTcraHYTcrbHY71VboTgTcraHYTcrbHY71VboE2f2tm1Zubi
• renal glomerulus hypertrophy_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0011294I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi
• increased susceptibility to autoimmune disorder_E2f2<tm1Zubi>/E2f2<tm1Zubi>
  http://metadb.riken.jp/0005350I129S1SvC57BL6E2f2tm1ZubiE2f2tm1ZubiE2f2tm1Zubi

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased T cell proliferation in RBRC06336
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1017608