Seiji. Inui, et.al., BCR signal through alpha 4 is involved in S6 kinase activation and required for B cell maturation including isotype switching and V region somatic hypermutation., International immunology, 2002, 14

http://rdf.ncbi.nlm.nih.gov/pubmed/11809737

Seiji. Inui, et.al., BCR signal through alpha 4 is involved in S6 kinase activation and required for B cell maturation including isotype switching and V region somatic hypermutation., International immunology, 2002, 14

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Igbp1<tm1Imku>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2656093

class

http://purl.org/net/cito/citesAsAuthority

• Igbp1<tm1Imku>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2656093

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased pre-B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Igbp1<tm1Imku>/Y
  http://metadb.riken.jp/0008209I129P2OlaHsdCd19tm1creCgnCd19Igbp1tm1ImkuYCd19tm1creCgnIgbp1tm1ImkuCd19
• abnormal B cell physiology_Cd19<tm1(cre)Cgn>/Cd19<+>,Igbp1<tm1Imku>/Y
  http://metadb.riken.jp/0002459I129P2OlaHsdCd19tm1creCgnCd19Igbp1tm1ImkuYCd19tm1creCgnIgbp1tm1ImkuCd19
• abnormal spleen germinal center morphology_Cd19<tm1(cre)Cgn>/Cd19<+>,Igbp1<tm1Imku>/Y
  http://metadb.riken.jp/0002359I129P2OlaHsdCd19tm1creCgnCd19Igbp1tm1ImkuYCd19tm1creCgnIgbp1tm1ImkuCd19
• decreased B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Igbp1<tm1Imku>/Y
  http://metadb.riken.jp/0005017I129P2OlaHsdCd19tm1creCgnCd19Igbp1tm1ImkuYCd19tm1creCgnIgbp1tm1ImkuCd19
• abnormal somatic hypermutation frequency_Cd19<tm1(cre)Cgn>/Cd19<+>,Igbp1<tm1Imku>/Y
  http://metadb.riken.jp/0004815I129P2OlaHsdCd19tm1creCgnCd19Igbp1tm1ImkuYCd19tm1creCgnIgbp1tm1ImkuCd19
• decreased B cell proliferation_Cd19<tm1(cre)Cgn>/Cd19<+>,Igbp1<tm1Imku>/Y
  http://metadb.riken.jp/0005093I129P2OlaHsdCd19tm1creCgnCd19Igbp1tm1ImkuYCd19tm1creCgnIgbp1tm1ImkuCd19
• decreased follicular B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Igbp1<tm1Imku>/Y
  http://metadb.riken.jp/0008174I129P2OlaHsdCd19tm1creCgnCd19Igbp1tm1ImkuYCd19tm1creCgnIgbp1tm1ImkuCd19
• decreased immunoglobulin level_Cd19<tm1(cre)Cgn>/Cd19<+>,Igbp1<tm1Imku>/Y
  http://metadb.riken.jp/0002460I129P2OlaHsdCd19tm1creCgnCd19Igbp1tm1ImkuYCd19tm1creCgnIgbp1tm1ImkuCd19